Carbon–carbon bond formation by sp–sp or sp–sp crosscoupling is a key transformation in organic synthesis. Many methods, typically involving transition metal catalysis, are known, and the recent recognition of Richard F. Heck, Ei-ichi Negishi and Akira Suzuki by the Royal Swedish Academy of Sciences (Stockholm, Sweden) when they were awarded the Nobel Prize in Chemistry (2010) underlines the im...

In the presence of catalytic [{IrCp*Cl2 }2 ] and Ag2 CO3 , Li2 CO3 as the base, and acetone as the solvent, benzoic acids react with arenediazonium salts to give the corresponding diaryl-2-carboxylates under mild conditions. This C-H arylation process is generally applicable to diversely substituted substrates, ranging from extremely electron-rich to electron-poor derivatives. The carboxylate d...

A mild visible-light-mediated strategy for cysteine arylation is presented. The method relies on the use of eosin Y as a metal-free photocatalyst and aryldiazonium salts as arylating agents. The reaction can be significantly accelerated in a microflow reactor, whilst allowing the in situ formation of the required diazonium salts. The batch and flow protocol described herein can be applied to ob...

An efficient and environmentally benign   method for the synthesis of aryl iodides have been developed by diazotization of aromatic amines with NaNO2 and nanosilica periodic acid (nano-SPIA) as a green catalyst via grinding followed by a sandmeyer iodination by KI under solvent-free conditions at room temperature. The ensuing aryl diazonium salts supported on nano-SPIA were sufficiently stable ...

Herein we present a mild, simple and environmentally friendly diazotization protocol of aromatic heteroaromatic anilines into stable diazonium salts that surpass previously reported procedures. The reaction proceeds with tert -butyl nitrite in the presence an equimolar amount or small excesses p -toluenesulfonic acid ethyl acetate, at room temperature. o -Phenylenediamines yield benzotriazolium...

We investigate poly(ethylene imine) and diazonium salts as stable, complementary dopants on graphene. Transport in graphene devices doped with these molecules exhibits asymmetry in electron and hole conductance. The conductance of one carrier is preserved, while the conductance of the other carrier decreases. Simulations based on nonequilibrium Green's function formalism suggest that the origin...

Activated carbon appended with organic groups was obtained by a grafting technique using a one-step reaction with diazonium salts. Using the organic aryl amines of 4-bromo aniline and 4-aminoantipyrine as precursors for the corresponding functional diazonium reagents, the bromobenzene and antipyrine molecules were bonded to the surface of carbon. The modified activated carbon was characterized ...