Neuroendocrine tumors are rarely seen in the breast. They are commonly located in the gastrointestinal tract and the lungs. These tumors of the breast may be purely neuroendocrine or neuroendocrine diff erentiated. Some breast tumors may have neuroendocrine foci. The clinical signifi cance of these tumors are unclear. However, they are thought to have no relation with the prognosis and patient ...

Neuroendocrine neoplasm of the larynx is a morphologically heterogeneous group of tumors. This unusual neoplasm includes the four different type of tumors. Paraganglioma is the best-known neural origin tumor. The epithelial origin tumor is further divided based on the degree of differentiation into well, moderately, and poorly differentiated carcinoma. The diverse biological behavior of neuroen...

BACKGROUND In 1999, large-cell neuroendocrine carcinoma of the lung was introduced by the World Health Organization (WHO) as a new tumor entity in the group of non-small cell, epithelial tumors, a differentiated classification of neuroendocrine tumors of the lung not existing until this time. Scientific knowledge on prognosis and therapy of these tumors, especially between those with neuroendoc...

Received 11/20/2009; revised 12/8/2009; accepted 12/10/2009. For correspondence and reprints contact: Yu-Chien Shiau, M.D.,Ph.D., Department of Nuclear Medicine, Far Eastern Memorial Hospital. 21 Section 2, Nan-Ya South Road, Panchiao, Taipei 22060, Taiwan. Tel: (886)2-89667000 ext. 1223, Fax: (886)2-89668378, E-mail: [email protected] Sinonasal neuroendocrine carcinoma is a rare malignant ne...

Rectal neuroendocrine carcinoma is rare with poor prognosis. We report herein a case of advanced moderately differentiated neuroendocrine carcinoma of the rectum with relatively favorable prognosis treated by postoperative adjuvant chemoradiation therapy. A 58-year-old Japanese female was referred and colonofiberscopy revealed an easybleeding irregular tumor in the lower rectum, which was patho...

We describe a rare hepatic collision tumor composed of a hepatocellular carcinoma and a high-grade neuroendocrine carcinoma. The patient, a 68-year-old man, underwent a partial hepatectomy because of a 4.0 cm mass. The tumor had two distinctive patterns. The majority of the tumor was a high-grade neuroendocrine carcinoma with features of a small cell carcinoma that was positive for chromogranin...

The system of classification and terminology neuroendocrine neoplasms (NENs), updated in 2017 by AJCC 2019 WHO, is now recommended for general use. This article a review this with respect to NENs the digestive tract. Within new system, two categories were introdu­ced, differing morphology, clinical course treatment, as based on differentiation histological maturity grading (G). Among tract, wel...

Neuroendocrine neoplasms are defined as epithelial neoplasms with predominant neuroendocrine differentiation. They can arise in almost every organ of the body although they are most commonly found in the gastrointestinal tract and respiratory system. Nasal cavity and paranasal sinuses are a rare site for neuroendocrine carcinoma. In contrast to the other regions, neuroendocrine tumours of the s...