Diffusion Tensor Magnetic Resonance Imaging (DT-MRI) is a specific modality of MRI which is based on the calculation of the diffusion of water along different directions within the brain. It can be used efficiently to map white matter tracts within the human brain. In previous work [1], we have shown how the Dual Tree Complex Wavelet Transform [2], [3] can be used to visualise DT-MRI data in 2 ...

Cardiac diffusion tensor MR imaging (DT-MRI) allows to analyze 3D fiber organization of the myocardium which may enhance the understanding of, for example, cardiac remodeling in conditions such as ventricular hypertrophy. Diffusion-weighted MRI (DW-MRI) denoising methods rely on accurate spatial alignment of all acquired DW images. However, due to cardiac and respiratory motion, cardiac DT-MRI ...

Traumatic injury to spinal cord affects thousands of persons and costs billions of dollars annually in treatment expenses. Although less than a decade ago spinal cord injury was thought of as an untreatable condition, many promising new treatments are now in the experimental stage. Rodent models are essential for validating new therapeutic trials. This paper presents results of in vivo magnetic...

Multiple sclerosis (MS), a demyelinating disease, occurs principally in the white matter (WM) of the central nervous system. Conventional magnetic resonance imaging (MRI) is sensitive to some, but not all, brain changes associated with MS. Diffusionweighted imaging (DWI) provides information about water diffusion in tissue and diffusion tensor MRI (DT-MRI) about fiber direction, allowing for th...

A second order tensor is usually used to describe the diffusion of water for each voxel within a Diffusion Tensor Magnetic Resonance (DT-MR) images. However, a second order tensor approximation fails to accurately represent complex local tissue structures such as crossing fibers. Therefore, higher order tensors are used to represent more complex diffusivity profiles. In this work we examine and...

Coherence-enhancing diffusion filtering is a striking application of the structure tensor concept in image processing. The technique deals with the problem of completion of interrupted lines and enhancement of flow-like features in images. The completion of line-like structures is also a major concern in diffusion tensor magnetic resonance imaging (DT-MRI). This medical image acquisition techni...

In order to achieve its main goal of maximal tumor removal while avoiding postoperative neurologic deficits, neuro-oncological surgery is strongly dependent on image guidance. Among all currently available imaging modalities, MRI provides the best anatomic detail and is highly sensitive for intracranial pathology. However, conventional MRI does not detect the exact location of white matter trac...

Diffusion tensor magnetic resonance imaging (DT-MRI) has previously been used to investigate white matter tracts in schizophrenia, with inconsistent results. The aim of the study was to use a novel method for tract-specific measurements of fronto-temporal fasciculi in early-onset schizophrenia. We hypothesized that by making tract-specific measurements, clear diffusion abnormalities would be re...

This study investigates water diffusion changes in Wallerian degeneration. We measured indices derived from the diffusion tensor (DT) and T2-weighted signal intensities in the descending motor pathways of patients with small chronic lacunar infarcts of the posterior limb of the internal capsule on one side. We compared these measurements in the healthy and lesioned sides at different levels in ...

J. T. Duda, H. Zhang, T. J. Simon, J. C. Gee Bioengineering, University of Pennsylvania, Philadelphia, PA, United States, Computer Science, University of Pennsylvania, Philadelphia, PA, United States, M.I.N.D. Institute, University of California, Davis, Davis, CA, United States, Radiology, University of Pennsylvania, Philadelphia, PA, United States Introduction Diffusion Tensor MRI (DT-MRI) has...