tranexamic acid is now used on a routine basis for on-pump coronary artery bypass grafting (cabg). we assessed the hemostatic effects of tranexamic acid to decrease bleeding tendency and transfusion requirements in patients undergoing off-pump coronary artery bypass surgery (opcab). a total of 66 patients were enrolled to elective opcab in a double-blind, prospective randomized study. of these,...

background: safe exclusion and risk stratification are currently recommended for the initial management of patients with acute pulmonary embolism (ape). the aim of this study was to assess the safe exclusion and risk stratification value of d-dimer (dd) for ape when tested at the beginning of admission. materials and methods: all consecutive chinese ape patients and controls were recruited from...

D-Dimer merupakan degrasi dari fibrin terlarut yang hasil degradasi sistematis thrombus vascular melalui mekanisme fibrinolitik. Tujuan penelitian ini adalah melihat faktor sosiodemografi dan penyakit lain mempengaruhi nilai d-dimer pasien covid-19. Penelitian menggunakan metode retrospective cohort dengan pengumpulan sampling convenience sampling. Terdapat 137 memenuhi kriteria penelitian. Umu...

The mechanism of cooperativity in the human hemoglobin tetramer (a dimer of alpha beta dimers) has historically been modeled as a simple two-state system in which a low-affinity structural form (T) switches, on ligation, to a high-affinity form (R), yielding a net loss of hydrogen bonds and salt bridges in the dimer-dimer interface. Modifications that weaken these cross-dimer contacts destabili...

Dimer models arise as effective descriptions in a variety of physical contexts, and provide paradigmatic examples systems subject to strong local constraints. Here we present quantum version the venerable Kasteleyn model, which has an unusual phase transition from dimer solid U(1) liquid. We show how structure model can be understood terms mechanics one-dimensional strings determine exact value...

dAn.dTn sequences, otherwise known as A tracts, are hotspots for cis-syn thymine dimer formation and deletion mutations induced by UV light. Such A tracts are also known to bend DNA, suggesting that some biological effects of UV light might be related to the distinctive structure and properties of cis-syn dimer-containing A tracts. To investigate the effect of thymine dimer formation on A-tract...

Fibrin degradation results in the formation of fibrin degradation products (FDPs) of different molecular weights, which include D-dimer. Commercial D-dimer assays recognize multiple forms of FDP with different specificity. As a result, the absence of an international D-dimer standard and the marked discrepancy in the D-dimer values in the same samples measured by assays from different manufactu...