نتایج جستجو برای: diosmin
تعداد نتایج: 193 فیلتر نتایج به سال:
This study was designed to investigate the structure of synthesized hesperidin glycosides (HGs) and evaluate their antibacterial α-glucosidase inhibitory activities. The preliminary HGs confirmed by glucoamylase treatment analyzed on thin layer chromatography (TLC). LC-MS/MS profiles showed important fragments at m/z ratios 345.21 (added glucose rutinose in HG1) 687.28 maltose HG2), confirming ...
The aim of this study was to investigate the clinical efficacy of oral Pycnogenol (Horphag Research Ltd., UK) in patients with severe chronic venous insufficiency (CVI) in comparison to the combination of diosmin and hesperidin (Daflon, Servier, France). A group of 86 patients with severe chronic venous insufficiency (CVI), venous hypertension, ankle swelling) and previous history of venous ulc...
A systematic study on the electrochemical behavior of diosmin in Britton-Robinson buffer (pH 2.0-10.0) at a glassy carbon electrode (GCE) was made. The oxidation process of the drug was found to be quasi-reversible with an adsorption-controlled step. The adsorption stripping response was evaluated with respect to various experimental conditions, such as the pH of the supporting electrolyte, the...
Purpose: This study aimed to evaluate the chemoprevention efficacy of diosmin on experimentally induced hamster buccal pouch (HBP) squamous cell carcinoma utilizing Ki 67 as a proliferative marker. Material and Methods: Seventy Syrian male hamsters were used experimental animals, these divided into five groups, Group I (negative control): 5 left untreated. II (DMBA treated group): 20 equally tw...
A rapid and sensitive spectrophotometric method for the determination of diosmin (D) has been developed. The method is based on the reaction of D with 4-aminoantipyrine (AAP) in the presence of hexacyanoferrate (III) (HCF) in an alkaline medium and subsequent formation of a purple coloured product having max at 524.5 nm. The conditions affecting the reaction (reagents concentration, pH, order o...
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