background: cardiovascular diseases are viewed worldwide as one of the main causes of death.this study aims to report the burden of ischemic heart diseases (ihds) in iran by using data of the global burden of disease (gbd) study, 1990-2010. materials and methods: the gbd study 2010 was a systematic eff ort to provide comprehensive data to calculate disability-adjusted life years (dalys) for dis...

OBJECTIVE We estimated the disability-adjusted life-year (DALY) burden of abusive head trauma (AHT) at ages 0 to 4 years in the United States. METHODS DALYs are computed by summing years of productive life that survivors lost to disability plus life-years lost to premature death. Surveying a convenience sample of 170 caregivers and pediatricians yielded health-related disability over time acc...

BACKGROUND AND PURPOSE Disability-adjusted life years (DALY), incorporating both disability and mortality, has been widely employed to measure regional and global burdens of stroke. Thus far, the DALY lost to stroke in a population has been estimated using only the crude population-level data; no previous study has incorporated refined data from stroke registries. The aim of this study was to i...

Background & Aims: The burden of premature mortality is used to prioritize health problems. The purpose of this study was to estimate the burden of premature mortality due to colorectal cancer in Golestan from 2011 – 2015. Materials & Methods: In this sequential cross-sectional study, based on the province mortality registration data and standard expected years of life lost (SEYLL), the burden...

BACKGROUND Sickle cell disease (SCD) constitutes a major public health problem in sub-Saharan Africa (SSA). Newborn screening and early subsequent clinical intervention can reduce early mortality and increase life expectancy, but have not been widely implemented in SSA. This analysis assesses the cost-effectiveness of a newborn screening and prophylactic intervention (NSPI) package for SCD in 4...