The lupus erythematosus cell (L.E. cell) phenomenon is usually regarded, if properly interpreted, as being almost specific for systemic lupus erythematosus (Wilkinson and Sacker, 1957). On the other hand, too rigid an outlook may lead to diagnostic errors or retard progress in the understanding of other diseases. Careful repeated examination of the blood of patients with classical rheumatoid ar...

Lupus erythematosus is an autoimmune disease that affects primarily women and whose cause is unknown. The diagnosis arises from a patient that may show singular signs or signs of a multisystem disease; there is a presence of autoantibodies, and other diseases with similar properties are ruled out. Two main forms of the disease exist; the discoid and the disseminated forms. Hippocrates was the f...

The patient was a 41-year-old woman with a 1-year history of systemic lupus erythematosus based on her discoid lupus erythematosus, photosensitivity, and her laboratory test findings that showed lymphopenia, low complement (C3, 38 mg/dL; C4, 4 mg/dL), and the presence of antinuclear antibody (1:320 speckled pattern) and antiphospholipid antibodies (anticardiolipin antibodies, anti-β2-glycoprote...

A female infant, born to a 21-year-old mother with systemic lupus erythematosus, had cutaneous discoid lupus at birth. The lesions resolved spontaneously over the first few months and by the age of 1 year the infant's skin was normal. Other possible complications of this maternal disease are discussed and the need for caution in counselling mothers is recommended.

OBJECTIVE To determine the demographic data, clinical pattern and therapeutic outcome in patients with discoid lupus erythematosus (DLE). STUDY DESIGN Case series. PLACE AND DURATION OF STUDY The Department of Dermatology, Liaquat University of Medical and Health Sciences, Jamshoro, from January 2004 to December 2008. METHODOLOGY Patients of either gender aged above 18 years diagnosed wit...

Malignant atrophic papulosis, commonly known as Degos disease, is a rare vasculopathy encompassing both benign, cutaneous and lethal systemic variants. We report a case of chronic cutaneous lupus erythematosus in a 41-year-old male presenting with prominent Degos-like skin lesions. Multiple atrophic, porcelain-white, scar-like papules and plaques with dusky, erythematous borders, suggestive of ...