Email networks in contemporary organizations are fairly representative of the underlying communications networks. We show that changes in communication networks have implications for studying organization disintegration. In this paper, we analyzed the changing communication network structure at Enron Corporation during the period of its disintegration (2000-2001). Our goal was to understand how...

The objective of this study was to compare the disintegration times among Canadian-marketed brand (alendronate 70 mg, alendronate 70 mg plus vitamin D 5600 IU, and risedronate 35 mg) and generic (Novo-alendronate 70 mg and Apo-alendronate 70 mg) once-weekly dosed bisphosphonates. All disintegration tests were performed with a Vanderkamp Disintegration Tester. Disintegration was deemed to have o...

This article is focused on the numerical analysis of the hard rock (ore) disintegration process (continuation of the firstly article published in this Journal, see [3]). The bit moves and sinks into the hard rock (mechanical contact with friction between the ore and the cutting bit) and subsequently disintegrates it. The disintegration (i.e. stress-strain relationship, contact forces, reaction ...

Aim of this research work was to develop mouth dissolving tablet that disintegrates rapidly in mouth by using tasteless complex of Levocetirizine and Tulsion-335. Effect of different parameters such as swelling time, resin activation, drug resin ratio as well as stirring time was optimized by taste and percentage drug loading. Formulated DRC (Drug Resin Complex) was characterized by infrared sp...

Mathematical modeling of anaerobic digestion (AD) is widely acknowledged as a powerful tool to v of the process and to support full-scale plant design, operation and optimization. In this work, a modified version of the IWA-ADM1 model is proposed to simulate the AD of tannery primary sludge (TPS) and fleshing, with special emphasis on the disintegration formulation. Multiple batch tests were pe...

The swelling behavior of disintegrating agents produced from microparticles of crosslinked, hydrophilic polymers was investigated as a function of time by using a swelling force measurement apparatus. The swelling force produced due to swelling of poly(acrylic acid-co-2-hydroxyethyl methacrylate) and poly(acrylic acid) was measured in various buffered solutions as a function of time and the swe...

Hydrogels with predictable degradation are highly desired for biomedical applications where timely disintegration of the hydrogel (e.g., drug delivery, guided tissue regeneration) is required. However, precisely controlling hydrogel degradation over a broad range in a predictable manner is challenging due to limited intrinsic variability in the degradation rate of liable bonds and difficulties ...

The objective of this research was to improve the dissolution of simvastatin and to incorporate it in rapid disintegrating tablets (RDTs) with an optimized disintegration and dissolution characteristics. Polyoxyethylene-polypropylene block copolymer (poloxamer 188) was employed as a hydrophilic carrier to prepare simvastatin solid dispersions (SDs). Fourier transform infrared spectroscopy, diff...