Introduction: Many kinetic studies have shown that sorption of metals on natural materials results in the formation of metal precipitates. However, the influence of temperature on the kinetic formation of these metal precipitates has not been studied. The effect of temperature on reaction rates is well known and important in understanding reaction mechanisms. For most reactions, the increase in...

Isothermal titration calorimetry is presented to be an excellent method of detecting lipid membrane solubilization upon the addition of detergents. As an example, the titration of the nan-ionic detergent C t2EOt, to the lipid POPC is studied. The main contribution to the measured titration heat is the detergent's enthalpy difference upon transfer between micelles and membranes. The detergent ad...

For increased analgesic effect, new composed tablets containing diclofenac sodium (DIC) with an addition of papaverine hydrochloride (PAP) were prepared to investigate the mechanism of release of the active substances from tablets with different excipients in eight different formulations. To detect the possible interactions between active substances and excipients differential scanning calorime...

In this work, poloxamer (PL)-based binary hydrogels, composed of PL 407 and PL 188, were studied with regard to the physicochemical aspects of sol-gel transition and pharmaceutical formulation issues such as dissolution-release profiles. In particular, we evaluated the cytotoxicity, genotoxicity, and in vivo pharmacological performance of PL 407 and PL 407-PL 188 hydrogels containing tramadol (...

Purpose: Albendazole is a poorly soluble drug which limits its oral bioavailability. The study was focussed to enhance the solubility by in-situ micronization. Methods: Albendazole microcrystals were prepared by solvent change method using gum karaya and hupu gum as stabilizing agents and the effect of each stabilizer on the prepared microcrystals were studied. FT-IR, DSC, XRD and SEM analysis ...

The objective of this study was to improve the stability and water-solubility of patchouli alcohol by complexing with β-cyclodextrin (β-CD). The interactions between patchouli alcohol and β-CD were characterized by differential scanning calorimetry (DSC), Fourier transformation-infrared (FT-IR) spectroscopy, powder X-ray diffraction (PXRD), and Scanning electron microscope (SEM), respectively. ...

This paper presents an experimental study on the dissolution kinetics and solvent extraction of total gold from Ijero-ekiti (Nigeria) gold ore deposit by hydrochloric acid leaching followed by extraction with Tributylphosphate (TBP) in kerosene. The leaching investigation showed that the gold ore dissolution in HCl solution increases with increasing acid concentration, temperature and with decr...

FeCO3 is present as a CO2 corrosion product in many industrial processes and takes part the natural mineralization process. This work presents solid–liquid equilibrium of system FeCO3-H2O at 5–120 °C. The solubility showed little temperature dependence. However, affected kinetics rate constants for dissolution increased with temperature. activation energy water was determined to 1.55 kJ mol−1. ...

We have performed a detailed study of the thermodynamics of the titration process in an isothermal titration calorimeter with full cells. We show that the relationship between the enthalpy and the heat measured is better described in terms of the equation Delta H = W(inj) + Q (where W(inj) is the work necessary to carry out the titration) than in terms of DeltaH = Q. Moreover, we show that the ...