Aqueous dissolution of silicate glasses and minerals plays a critical role in global biogeochemical cycles and climate evolution. The reactivity of these materials is also important to numerous engineering applications including nuclear waste disposal. The dissolution process has long been considered to be controlled by a leached surface layer in which cations in the silicate framework are grad...

The commonly held model for membrane dissolution by detergents/surfactants requires lipid transport from the inner to the outer bilayer leaflet ('flip-flop'). Although applicable to many systems, it fails in cases where cross-bilayer transport of membrane components is suppressed. In this paper we investigate the mechanism for surfactant-induced solubilization of polymeric bilayers. To that end...

Dissolution of voids is a classical problem in the theory of sintering. The foundations of the theory were established by Frenkel, Pines and Geguzin (see Refs. 1 and 2 for a review). However, an important aspect of the problem appears to have been overlooked by previous workers. In a recent paper, the present authors identified a mechanism which inhibits processes associated with vacancy genera...

Aerosol particles deposited in the lungs that are not readily soluble in the epithelial lining fluid will be phagocytized by alveolar macrophages (AM). Inside the phagolysosomal vacuole, the constituents of the plasma allow dissolution of a variety of compounds at a higher rate than dissolution in extracellular lung fluids. Chelator concentration and a pH value of about 5 were found to control ...

The aims of this study are to increase and explain the mechanism of dissolution enhancement of isradipine using the sonoprecipitation method for stable nanosuspensions. There have been still few of published researches on formulation of isradipine using nanoparticle engineering. Nanosuspension systems were prepared upon various factors including amplitude and the time length of ultrasonication....

Copyright © 2014 by The Geochemical Society of Japan. Strandh et al., 1997), reactivity of different surface sites (e.g., Blum and Lasaga, 1988, 1991; Blum et al., 1990; Dove, 1994; Furrer and Stumm, 1986; Lasaga, 1992; Pelmenschikov et al., 2000; Raghavachari and Rohlfing, 1991; Bickmore et al., 2008; Wallace et al., 2010), the extent of undersaturation of the solution (e.g., Dove et al., 2005...

The effect of antacids on the dissolution behaviour of methacycline and doxycycline capsules from commercial dosage forms were studied. The dissolution of both tetracyclines was found to be markedly retarded by antacids such as magnesium trisilicate and magnesium oxide. An attempt was made to elucidate the mechanism of this effect. The results suggest that the effect of antacids on the dissolut...

The purpose of this study was to develop a compaction technique to enhance the solubility, dissolution rate and other physicochemical properties of poorly water-soluble drug indomethacin (IM) with different polymers. The IM was compacted with the different polymers like hydroxy propyl methylcellulose (HPMC), Kollicoat IR, Chitosan, Polyvinyl Pyrrolidone without using any binder and solvent. Pol...