The plasmid/liposome (PL) delivery of the manganese superoxide dismutase (MnSOD) transgene to lung, esophagus, oral cavity, bladder, or delivery of the same transgene by viral vectors including Herpes virus, adenovirus, and retrovirus to cells in culture or to intestine have been demonstrated to confer cellular and tissue resistance to ionizing iradiation damage including apoptosis. In contrast...

Ionising radiation (IR) is responsible for various types of tissue injury leading to morbidity at low doses and mortality at high radiation exposure. Although many radioprotective and pharmacological agents are being tested for decreasing radiation injury, however, the availability of Amifostine as the only clinically used radioprotector with limited indication has prompted us to find out new p...

Certifying professionals in radioprotection (RP), according to the requirements and qualifications established current Brazilian legislation, ensures that procedures practices radiology, radiotherapy nuclear medicine be performed based on fundamental principles of radioprotection. However, none regulations resolutions country involving use ionizing radiation, qualification RP for interventional...

ACE inhibitors and ARBs (angiotensin receptor blockers) have been shown to attenuate radiation injuries in animal models of lethal gamma irradiation. These two classes of drug act by curtailing the actions of angiotensin II-linked inflammatory pathways that are up-regulated during gamma radiation in organ systems such as the brain, lung, kidney, and bone marrow. ACE inhibitors inhibit ACE and a...

Microbial melanins provide a biocompatible and scalable approach for bioremediation and radioprotection technologies due to their physicochemical properties.