نتایج جستجو برای: donepezil hydrochloride

تعداد نتایج: 45696  

Journal: :Archives of general psychiatry 2011
Charles F Reynolds Meryl A Butters Oscar Lopez Bruce G Pollock Mary Amanda Dew Benoit H Mulsant Eric J Lenze Margo Holm Joan C Rogers Sati Mazumdar Patricia R Houck Amy Begley Stewart Anderson Jordan F Karp Mark D Miller Ellen M Whyte Jacqueline Stack Ariel Gildengers Katalin Szanto Salem Bensasi Daniel I Kaufer M Ilyas Kamboh Steven T DeKosky

CONTEXT Cognitive impairment in late-life depression is a core feature of the illness. OBJECTIVE To test whether donepezil hydrochloride and antidepressant therapy is superior to placebo and antidepressant therapy in improving cognitive performance and instrumental activities of daily living and in reducing recurrences of depression over 2 years of maintenance treatment. DESIGN Randomized, ...

Journal: :Osaka city medical journal 2011
Aiko Shimada Hiroshi Hashimoto Joji Kawabe Shigeaki Higashiyama Toshihiro Kai Kouhei Kataoka Ryo Tagawa Youjirou Kawarada Aki Nakanishi Koki Inoue Susumu Shiomi Nobuo Kiriike

BACKGROUND Donepezil hydrochloride (Donepezil) is an acetylcholinesterase inhibitor (AChEI) that is used for the symptomatic treatment of Dementia of the Alzheimer's Type (DAT). Recently, the effects of AChEI in patients with DAT have been investigated using positron emission tomography (PET) or single photon emission computed tomography (SPECT). This study is to evaluate the usefulness of fluo...

2017
Yujie Jia Xuezhu Zhang Jianchun Yu Jingxian Han Tao Yu Jiangwei Shi Lan Zhao Kun Nie

BACKGROUND Alzheimer's disease (AD) is the most common cause of dementia. However, none of medical treatment can stop or reverse the underlying neurodegenerative of AD at present. Acupuncture has attracted more and more attention in recent years due to its efficacy and very few side effects. Lately, a systematic review has thought that the evidence on the effectiveness of acupuncture in improvi...

Journal: :Neurobiology of aging 2011
Norbert Schuff Joyce Suhy Robert Goldman Yikang Xu Yijun Sun Diana Truran-Sacrey Anita Murthy

A magnetic resonance imaging (MRI) study was conducted as part of an intervention study in subjects with amnestic mild cognitive impairment (aMCI) to assess donepezil's treatment effect on brain atrophy. Adults with aMCI were randomly assigned to double-blind treatment with 10 mg/day donepezil hydrochloride or placebo for 48 weeks. Brain MRI scans were acquired at baseline and endpoint. The pri...

Background: Accumulation of amyloid-β (Aß) plaques, primarily in the hippocampus, leads to neuronal death and Alzheimer disease. Exercise and medications can prevent and treat neuronal diseases. This study aimed to determine the effects of aerobic training and donepezil, a medication used in Alzheimer disease, on the improvement of learning and memory deficits in Aß-injected male rats. Methods...

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