donor selection

Stephen R Spellman Mary Eapen Brent R Logan Carlheinz Mueller Pablo Rubinstein Michelle I Setterholm Ann E Woolfrey Mary M Horowitz Dennis L Confer Carolyn K Hurley

Selection of a suitable graft for allogeneic hematopoietic stem cell transplantation involves consideration of both donor and recipient characteristics. Of primary importance is sufficient donor-recipient HLA matching to ensure engraftment and acceptable rates of GVHD. In this Perspective, the National Marrow Donor Program and the Center for International Blood and Marrow Transplant Research pr...

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Associations of health status with subsequent blood donor behavior—An alternative perspective on the Healthy Donor Effect from Donor InSight

2017

Katja van den Hurk Saurabh Zalpuri Femmeke J Prinsze Eva-Maria Merz Wim L A M de Kort

INTRODUCTION In donor health research, the 'Healthy Donor Effect' (HDE) often biases study results and hampers their interpretation. This refers to the fact that donors are a selected 'healthier' subset of a population due to both donor selection procedures and self-selection. Donors with long versus short donor careers, or with high versus low donation intensities are often compared to avoid t...

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