background: to enhance the dose to tumor, the use of high atomic number elements has been proposed. objective: the aim of this study is to investigate the effect of gold nanoparticle distribution on dose enhancement in tumor when the tumor is irradiated by typical monoenergetic x-ray beams by considering homogeneous and inhomogeneous distributions of gold nanoparticles (gnps) in the tumor. meth...

To evaluate the utility of Dynalog file information for planar dose verification in IMRT QA, a program is developed to convert Dynalog file data to DMLC field files. For this study, five predefined fluencies are planned and delivered using Varian, Eclipse 3D planning system and 6MV photon beam of Varian, Clinac DMX linear accelerator. To measure planar dose distribution, Kodak, EDR2 films are e...

Introduction Polymer gel dosimeters offer a practical solution to 3D dose verification for conventional radiotherapy as well as intensity-modulated and stereotactic radiotherapy. In this study, EGSnrc calculated and PAGAT polymer gel dosimeter measured dose profiles from single shot irradiation with 18 mm collimator of Gamma Knife in homogeneous and inhomogeneous phantoms were compared with eac...

BACKGROUND Conventional phantom-based planar dosimetry (2D-PBD) quality assurance (QA) using gamma pass rate (GP (%)) is inadequate to reflect clinically relevant dose error in intensity-modulated radiation therapy (IMRT), owing to a lack of information regarding patient anatomy and volumetric dose distribution. This study aimed to evaluate the dose distribution accuracy of IMRT delivery for na...

introduction polymer gel dosimeters offer a practical solution to 3d dose verification for conventional radiotherapy as well as intensity-modulated and stereotactic radiotherapy. in this study, egsnrc calculated and pagat polymer gel dosimeter measured dose profiles from single shot irradiation with 18 mm collimator of gamma knife in homogeneous and inhomogeneous phantoms were compared with eac...

The three-dimensional dose (3D) distribution of intensity-modulated radiation therapy (IMRT) was verified based on electronic portal imaging devices (EPIDs), and the results were analyzed. Thirty IMRT plans of different lesions were selected for 3D EPID-based dose verification. The gamma passing rates of the 3D dose verification-based EPID system (Edose, Version 3.01, Raydose, Guangdong, China)...

A three-dimensional (3D) intensity-modulated radiotherapy (IMRT) pretreatment verification procedure has been developed based on the measurement of two-dimensional (2D) primary fluence profiles using an amorphous silicon flat-panel electronic portal imaging device (EPID). As described in our previous work, fluence profiles are extracted from EPID images by deconvolution with kernels that repres...

Inter- and intra-fractional prostate motion can deteriorate the dose distribution in extremely hypofractionated intensity-modulated proton therapy. We used verification CTs data calculated from 1024 records to develop a voxel-wise based 4-dimensional method, which had time resolution of 1 second, assess impact motion. An example 100 fractional simulations revealed that minimal on planning dose,...

In this paper the various approaches of EPID-based in vivo IMRT and VMAT dose verification, and their clinical implementation, are described. It will be shown that EPID-based in vivo dosimetry plays an important role in the total chain of verification procedures in a radiotherapy department. EPID-based dosimetry, in combination with in-room imaging, is a fast and accurate tool for 3D in vivo ve...

Introduction: Tumor control and treatment quality depend on accuracy of delivered dose. Various methods have been studied for treatment dosimetry verification. Among these methods, the use of electronic portal imaging device (EPID) is highly considered. Many efforts are underway to improve the results of this context.   Materials and Methods: In this study, ...