Aim: Calculating the absorbed dose is important for the determination of risk and therapeutic benefit of internal radiation therapy. Optimal dose estimations require time-consuming and sophisticated methods, which are difficult due to practical reasons. To make dosimetry available for each of the patients, we developed a specific dosimetry procedure used in daily clinical routine. Materials and...

The therapeutic use of radioisotopes in medicine as unsealed sources has a long history dating back to the 1930s. The established and continuing objectives are to provide radiation dose to the target tissue at the desired cytotoxic level while avoiding or minimizing toxic effects. Selected radionuclide therapy protocols including 32P for polycythemia vera, 131I for Graves' disease, and 131I for...

Current estimation of radiation dose from computed tomography (CT) scans on patients has relied on the measurement of Computed Tomography Dose Index (CTDI) in standard cylindrical phantoms, and calculations based on mathematical representations of "standard man". Radiation dose to both adult and pediatric patients from a CT scan has been a concern, as noted in recent reports. The purpose of thi...

BNCT incorporates the targeting principles of chemotherapy and the anatomical localization principles of conventional radiotherapy but with three distinct advantages:  Current boron compounds at the required concentrations are non-toxic.  The time interval between drug administration and neutron irradiation can be chosen to maximize the concentration differential between tumour and normal tis...

background: small photon fields are increasingly used in modern radiotherapy especially in intensity modulated radiation therapy (imrt) and stereotactic radiosurgery (srs) treatments. accurate beam profile and central axis depth doses measurements of such beams are complicated due to the electron disequilibrium. hence the ebt2 (external beam therapy) gafchromic film was used for dosimetry of sm...

Introduction The Gamma Knife system is designed solely for non-invasive treatment of brain disorders, and it benefits from stereotactic surgical techniques. Dose calculations required in the system are performed by GammaPlan code; in this code, brain tissue is considered uniform. In the present study, we evaluated the effect of Gamma Knife system on the obtained dose through simulating a real ...

Background: Attenuation coefficient (μ) plays an important role in calculations of treatment planning systems, as well as determination of dose distributions in external beam therapy, dosimetry, protection, phantom materials and industry. So, its exact measurement or calculation is very important. The aim of this study was to evaluate the μ in different points in the water phantom anal...

....................................................................................................................................................... iii List of Tables ................................................................................................................................................ vi List of Figures .................................................................

background: accurate small radiation field dosimetry is essential in modern radiotherapy techniques such as stereotactic radiosurgery (srs) and intensity modulated radiotherapy (imrt). precise measurement of dosimetric parameters such as beam profile, percentage depth doses and output factor of these beams are complicated due to the electron disequilibrium and the steep dose gradients. in the p...