BACKGROUND A previous study from our laboratory showed that polybrominated diphenyl ethers (PBDEs) were metabolized to hydroxylated PBDEs (HO-PBDEs) in mice and that para-HO-PBDEs were the most abundant and, potentially, the most toxic metabolites. OBJECTIVE The goal of this study was to determine the concentrations of HO-PBDEs in blood from pregnant women, who had not been intentionally or o...

An extension of the planar Smale-Birkhoff homoclinic theorem to the case of a heteroclinic saddle connection containing a finite number of fixed points is presented. This extension is used to find chaotic dynamics present in certain time-periodic perturbations of planar fluid models. Specifically, the Kelvin-Stuart cat's eye flow is studied, a model for a vortex pattern found in shear layers. A...

Purpose: The objective of this study was to determine the fate of the Ho-chitosan complex (DW-166HC) in rats by examining its absorption, distribution and excretion after administration into the prostate. Methods: About 100 Ci of DW-166HC [containing 0.1875 mg of Ho(NO3)3·5H2O and 0.25 mg of chitosan] was administered intraprostatically. The level of radioactivity in blood, urinary and faecal e...

Recent in vivo and in vitro experiments indicated that methoxylated polybrominated diphenyl ethers (MeO-PBDEs) can be biotransformed into hydroxylated PBDEs (HO-PBDEs) that are more toxic than PBDEs and MeO-PBDEs. Nevertheless, the enzymatic transformation mechanism is not clear. We hypothesized that cytochrome P450 enzymes (CYPs) play a key role in the transformation and employed the density f...

Stillbirth (SB) often results in reduced milk yield, compromised reproductive performance, and decreased dam longevity. Corrective mating can be used as a short-term solution to the problem, but long-term improvement of the population requires the routine calculation of genetic evaluations. Breeding values for SB have been available for Holstein (HO) bulls since 2006, but not for Brown Swiss (B...

A time-reversal-violating spin-correlation coefficient in the total cross section for polarized neutrons incident on a tensor rank-2 polarized target is calculated by assuming a time-reversal-noninvariant, parity-conserving “five-fold” interaction in the neutron-nucleus optical potential. Results are presented for the system n + Ho for neutron incident energies covering the range 1–20 MeV. From...

The present article deals with the structurally, spectroscopically and electrochemically characterised osmium-bipyridyl derived complexes [(bpy)2Os(II)(HL1)Cl]ClO4 [1]ClO4 and [(bpy)2Os(II)(HL2)Cl]ClO4 [2]ClO4 incorporating neutral and monodentate pyrazole derivatives (HL) with one free NH function (bpy = 2,2'-bipyridine, HL1 = pyrazole, HL2 = 3,5-dimethylpyrazole). The crystal structures of [1...

The mechanism of cis-dihydroxylation of nitrobenzene and 2-nitrotoluene catalyzed by nitrobenzene 1,2-dioxygenase (NBDO), a member of the naphthalene family of Rieske non-heme iron dioxygenases, was studied by means of the density functional theory method using four models of the enzyme active site. Different possible reaction pathways for the substrate dioxygenation initiated either by the Fe(...

in a patient with mixed connective tissue disease: An unusual complication. Lupus. 2010;19:1005--6. 12. Falchi L, Capello D, Palumbo B, Rauco A, Emili R, Cianciulli M, et al. A case of nodular sclerosis Hodgkin’s lymphoma repeatedly relapsing in the context of composite plasma cell-hyaline vascular Castleman’s disease: Successful response to rituximab and radiotherapy. Eur J Haematol. 2007;79:4...

Objective. The asymmetry ratio of ocular vestibular-evoked myogenic potential (oVEMP) >40% is interpreted as augmented or reduced response depending on whether the nI-pI amplitude of the lesion ear is larger or smaller than that of the opposite ear, respectively. This study compared unilateral Ménière disease patients with augmented oVEMPs vs reduced oVEMPs to elucidate the mechanism of augment...