The effects of verapamil were assessed in 26 patients with stable exertional angina pectoris in a double-blind, placebo-controlled, randomized crossover protocol using serial treadmill tests. Verapamil, 480 mg/day, reduced anginal frequency from 5.6 +/- 7.3 to 2.2 +/- 3.9 attacks per week (p less than 0.001) and nitroglycerin consumption from 3.4 +/- 4.9 to 1.2 +/- 2.5 tablets per week (p less ...

In 18 patients with stable effort angina, verapamil, 80 mg four times daily, was compared with propranolol, 80 mg four times daily, in a double-blind, placebo-controlled trial to assess the effects on anginal threshold, exercise capacity and left ventricular function measured by gated equilibrium blood pool scanning. Both propranolol and verapamil improved exercise capacity (placebo 424 +/- 135...

Does a performance measure which is a monotonous function of the benefit (a benefit measure) lead to a desirable allocation of effort between the tasks which create this benefit? We analyse two settings. If the mechanism designer knows the choice set of the agent, benefit measures generally do not result in the second-best effort allocation – unless restrictive assumptions about agent’s prefere...

In this paper we discuss technology appropriation in the context of close personal relationships. We review literature that reveals how collaborative appropriation is a natural and necessary feature of technology adoption by relational partners. We then advance a position whereby appropriations in close relationships can be characterised as a form of discretionary effort investment. We end by r...

This article draws on the ‘double indeterminacy of labour power’, a key conceptual development in process theory, to examine mobility power Saudi Arabia. State control over migrant workers is crucial and wider political-economy However, little known about mobility–effort bargaining specific forms context. argues that not only at core capital–labour relations Arabia, but effort are variably cont...