The embryos of teleost fish are exquisitely sensitive to the toxic effects of exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). However, several lines of evidence suggest that adults are less sensitive to TCDD. To better understand and characterize this difference between early life stage and adults, we exposed zebrafish (Danio rerio) to graded TCDD concentrations at different ages. The L...

Histone tail modifications control many nuclear processes by dictating the dynamic exchange of regulatory proteins on chromatin. Here we report novel insights into histone H3 tail structure in complex with the double PHD finger (DPF) of the lysine acetyltransferase MOZ/MYST3/KAT6A. In addition to sampling H3 and H4 modification status, we show that the DPF cooperates with the MYST domain to pro...

Kim, HyoJeong. M.S., Purdue University, December, 2003. Performance Evaluation of Route-based Distributed Packet Filtering for DDoS Prevention in Large-scale Networks. Major Professor: Kihong Park. This thesis studies performance evaluation of route-based distributed packet filtering (DPF) for spoofed distributed denial of service (DDoS) attack prevention in large-scale networks under dynamic n...

Foxl2 is essential for mammalian ovary maintenance. Although sexually dimorphic expression of foxl2 was observed in many teleosts, its role and regulative mechanism in fish remained largely unclear. In this study, we first identified two transcript variants of foxl2a and its homologous gene foxl2b in zebrafish, and revealed their specific expression in follicular layer cells in a sequential and...

Light plays a key role in synchronizing rhythms and setting the phase of early development. However, to date, little is known about the impact of light wavelengths during the ontogeny of the molecular clock and the behavioural rhythmicity. The aim of this research was to determine the effect of light of different wavelengths (white, blue and red) on the onset of locomotor activity and clock gen...

Oxidative stress is an important mechanism of chemical toxicity, contributing to teratogenesis and to cardiovascular and neurodegenerative diseases. Developing animals may be especially sensitive to chemicals causing oxidative stress. The developmental expression and inducibility of anti-oxidant defenses through activation of NF-E2-related factor 2 (NRF2) affect susceptibility to oxidants, but ...

In ectotherm species, environmental temperature plays a key role in development, growth, and survival. Thus, determining how affects fish populations is of utmost importance to accurately predict the risk climate change over fisheries aquaculture, critical warrant nutrition food security coming years. Here, potential effects abnormal thermal regimes (24, 28 32 °C; TR24, TR28, TR32, respectively...

The abatement of the pollutants deriving from diesel engines in vehicle sector still represents an interesting scientific and technological challenge due to increasingly limiting regulations. Meeting stringent limits NOx soot emissions requires a catalytic system with great complexity, size units, number as well increased fuel consumption. Thus, after-treatment device for use integrated catalys...

This study was conducted to evaluate the effects of a diesel particulate filter (DPF) regeneration process on the concentrations and size distributions of aerosols in an underground mine. Two active regeneration strategies were examined for an electrically regenerated sintered metal fiber filtration system, and the effects were compared with those observed for a muffler and the same system oper...

In this paper, we present a distributed particle filter (DPF) for target tracking in a sensor network. The proposed DPF consists of two major steps. First, particle compression based on support vector machine is performed to reduce the cost of transmission among sensors. Second, each sensor fuses the compressed information from its neighboring nodes with use of consensus or gossip algorithm to ...