Recent years have seen a marked diversification of excipient based formulation strategies used for the development and commercialisation of dry powder inhaler (DPI) products. These innovative approaches not only provide benefits to patients and health care professionals through the availability of a wider range of therapeutic DPI products, but, importantly, also allow formulators to exploit the...

We report on the photon energy dependence of the K-shell double photoionization (DPI) of Mg, Al, and Si. The DPI cross sections were derived from high-resolution measurements of x-ray spectra following the radiative decay of the K-shell double vacancy states. Our data evince the relative importance of the final-state electron-electron interaction to the DPI. By comparing the double-to-single K-...

Focal and diffuse neuronal loss happened after traumatic brain injury (TBI). With little in the way of effective repair, recent interest has focused on endogenic neural progenitor cells (NPCs) as a potential method for regeneration. Whether endogenic neural regeneration happened in the cortex of adult rat after TBI remains to be determined. In this study, rats were divided into a sham group and...

The efficacy of nitazoxanide (NTZ) against toxocariasis was investigated in an experimental murine model and results were compared to those obtained using mebendazole. Sixty male BALB/c mice, aged six to eight weeks-old, were divided into groups of 10 each; fifty were orally infected with 300 larvaed eggs of T. canis and grouped as follows, G I: infected untreated mice; G II: infected mice trea...

D EEP packet inspection (DPI) examines the content in packet payloads to search for signatures of network applications, signs of malicious activities, and leaks of sensitive information, rather than just examine packet headers for information such as IP addresses and port numbers. The inspection provides network devices with rich information of application protocol messages in packet payloads, ...

avian infectious bronchitis (ib) is a major cause of economic losses in poultry industry. the ib virus primarily affects respiratory tract, but various strains differ in their tropism for other target organs such as kidney and alimentary tract. the objective of this study was to estimate the pathogenicity of iranian ibv variant (ir-1), which is limited exclusively to iran. specific pathogen fre...

The analysis of packet payload is mandatory for network security and traffic monitoring applications. The computational cost of this activity pushed the industry towards hardware-assisted deep packet inspection (DPI) that have the disadvantage of being more expensive and less flexible. This paper covers the design and implementation of a new DPI framework using FastFlow, a skeleton-based parall...

The DPI model (Documents, Presentations, Instruments) offers an alternative to current application-centered environments by introducing a conceptual model based on documents and interaction instruments. DPI makes it possible to edit a document through multiple simultaneous presentations. The same instrument can edit different types of content, facilitating interaction and reducing the user's co...

The progress in the development of DPI technology has boosted the use of sensitive drug molecules for lung diseases. However, delivery of these molecules from conventional DPI to the active site still poses a challenge with respect to deposition efficiency in the lung. At same time, serious systemic side effects of drugs have become a cause for concern. The developed budesonide loaded biopolyme...