Background and objectives: Dracocephalum species are mentioned in Iranian traditional medicine for enhancement of cognitive performance. In the present study, the acetyl cholinesterase inhibitory and butyryl cholinesterase inhibitory activities as well as the anti-oxidant and anti-tyrosinase effects of three Iranian Dracocephalum species (D. kotschyi,...

The health benefits of Dracocephalum heterophyllum are widely reported in traditional Tibetan medicines, but the chemical composition is limited, probably due to difficulties separating and purifying compounds. In this study, antioxidative phenylethanoids were isolated from an extract using medium- high-pressure liquid chromatography, coupled with on-line HPLC–1,1-diphenyl-2-picrylhydrazyl reco...

Trypanocidal activity was found in the volatile oil of dried Dracocephalum kotschyi. GC-MS analysis determined that the major constituents of the oil were geranial (35.8%), C10H14O (26.6%), limonene (15.8%) and 1,1-dimethoxy decane (14.5%). In order to isolate the unknown biologically active monoterpene, fractionation of the volatile oil was carried out by silica gel column chromatography. The ...

From the whole plant of Dracocephalum kotschyi BOISS., two new monoterpene glycosides (9, 10), together with seven known terpenoids and a phytosterol (1-8), were isolated. Their structures were determined to be limonen-10-al (1), geranial (2), neral (3), beta-sitosterol (4), oleanolic acid (5), ursolic acid (6), p-mentha-8-en-1,2-diol (7), colosolic acid (8), limonen-10-ol 10-O-beta-D-glucopyra...

objective: dracocephalum kotschyi (lamiaceae family) has been usedin traditional medicine for stomach and liver disorders, headache and congestion. in the present study, we have investigated phytochemical properties and antioxidant activities of dichloromethane, ethyl acetate and methanol extracts of d.kotschyi. material and methods: antioxidant activities of extracts were evaluated using the i...

Objective(s) Dracocephalum moldavica (D. moldavica) have been traditionally used as a cardiotonic agent in the folk medicine of some regions of Iran. In the present study, effects of total extract of D. moldavica on ischemia/reperfusion induced arrhythmias and infarct size investigated in isolated rat heart. Materials and Methods The isolated hearts were mounted on a Langendorff apparatus then ...