نتایج جستجو برای: drc

تعداد نتایج: 1633  

Journal: :Carcinogenesis 2008
Somdat Mahabir Qingyi Wei Stephanie L Barrera Yong Quan Dong Carol J Etzel Margaret R Spitz Michele R Forman

Magnesium (Mg) is required for maintenance of genomic stability; however, data on the relationship between dietary Mg intake and lung cancer are lacking. In an ongoing lung cancer case-control study, we identified 1139 cases and 1210 matched healthy controls with data on both diet and DNA repair capacity (DRC). Dietary intake was assessed using a modified Block-NCI food frequency questionnaire ...

Journal: :Journal of animal science 2012
K E Hales N A Cole J C MacDonald

The growing ethanol industry in the Southern Great Plains has increased the use of wet distillers grains with solubles (WDGS) in beef cattle (Bos taurus) finishing diets. Few studies have used steam-flaked corn (Zea mays L.; SFC)-based diets to evaluate the effects of WDGS in finishing cattle diets, and a reliable estimate of the net energy value of WDGS has yet to be determined. Effects of cor...

2017
Tomohiro Kubo Toshiyuki Oda

Tubulins undergo various posttranslational modifications. Among them, polyglutamylation is involved in the motility of eukaryotic flagella and the stability of the axonemal microtubules. However, it remains unclear where polyglutamylated tubulin localizes precisely within the axoneme and how tubulin polyglutamylation affects flagellar motility. In this study, we identified the three-dimensional...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2012
Jana Slyskova Vlasta Korenkova Andrew R Collins Pavel Prochazka Ludmila Vodickova Jiri Svec Ludmila Lipska Miroslav Levy Michaela Schneiderova Vaclav Liska Lubos Holubec Rajiv Kumar Pavel Soucek Alessio Naccarati Pavel Vodicka

PURPOSE DNA repair capacity (DRC) is a determinant not only of cancer development but also of individual response to therapy. Previously, altered base and nucleotide excision repair (BER and NER) have been described in lymphocytes of patients with sporadic colorectal cancer. We, for the first time, evaluate both excision repair capacities in human colon biopsies to study their participation in ...

Journal: :Journal of animal science 2009
M E Corrigan G E Erickson T J Klopfenstein M K Luebbe K J Vander Pol N F Meyer C D Buckner S J Vanness K J Hanford

Two experiments were conducted to determine the effect of corn processing method and corn wet distillers grains plus solubles (WDGS) level on steer performance and metabolism. In Exp. 1, 480 crossbred steer calves (314 +/- 18 kg of BW) were used in a finishing experiment with a randomized complete block design and a 3 x 4 treatment structure. Diets were based on dry-rolled (DRC), high-moisture ...

Journal: :British journal of haematology 2017
Jonas Paludo Jithma P Abeykoon Shaji Kumar Amanda Shreders Sikander Ailawadhi Morie A Gertz Taxiarchis Kourelis Rebecca L King Craig B Reeder Nelson Leung Robert A Kyle Francis K Buadi Thomas M Habermann David Dingli Thomas E Witzig Angela Dispenzieri Martha Q Lacy Ronald S Go Yi Lin Wilson I Gonsalves Rahma Warsame John A Lust S Vincent Rajkumar Stephen M Ansell Prashant Kapoor

The management of Waldenström macroglobulinaemia (WM) relies predominantly on small trials, one of which has demonstrated activity of dexamethasone, rituximab and cyclophosphamide (DRC) in the frontline setting. We report on the efficacy of DRC, focusing on relapsed/refractory (R/R) patients. Ibrutinib, a recently approved agent in WM demonstrated limited activity in patients with MYD88WT genot...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه پیام نور - دانشگاه پیام نور استان تهران - دانشکده کشاورزی و منابع طبیعی 1389

هدف از انجام این پژوهش بررسی مزیت نسبی محصولات کشاورزی در بخش ماهان از توابع استان کرمان می باشد.برای محاسبه شاخص های مزیت نسبی وآثار سیاستی از ماتریس تحلیل سیاستی(pam) استفاده شده است. این شاخص ها شامل هزینه منابع داخلی(drc )،هزینه به منفعت اجتماعی(scb)،ضریب حمایت اسمی از نهاده ها (npic)،حمایت اسمی از بازار محصول(npc)،حمایت موثر از محصول(epc) و سودآوری خالص اجتماعی(nsp) است.اطلاعات میدانی با ا...

Journal: :Journal of the National Cancer Institute 2002
Carol H Bosken Qingyi Wei Christopher I Amos Margaret R Spitz

BACKGROUND Non-small-cell lung cancer (NSCLC) is frequently resistant to chemotherapy, and this resistance has been associated with elevated nucleotide excision repair (NER) in tumor tissue. We hypothesized that patients with NSCLC who had effective systemic (host) NER would have poorer survival than patients with suboptimal NER and that the association between NER effectiveness and survival wo...

Journal: :Cancer research 2001
M R Spitz X Wu Y Wang L E Wang S Shete C I Amos Z Guo L Lei H Mohrenweiser Q Wei

Sequence variations have been identified in a number of DNA repair genes, including XPD, but the effect of these polymorphisms on DNA repair capacity (DRC) is uncertain. We therefore examined XPD polymorphisms at Lys751Gln and Asp312Asn in 341 white lung cancer cases and 360 age-, sex-, ethnicity-, and smoking-matched controls accrued in a hospital-based molecular epidemiological study of susce...

Journal: :Postgraduate medical journal 1992
M Offringa J Benbassat

The proportion of dysmorphic red cells (DRC) in the urinary sediment and their mean corpuscular volume (MCV) have been claimed to discriminate between glomerular and postglomerular sources of haematuria. To determine the diagnostic value of urinary DRC and MCV, we searched the literature and critically reviewed 21 published studies using a predetermined set of criteria for evaluation. All studi...

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