more recently medical chemistry research has been focused on proteins that drive and controlcell cycle progression. among them, the cyclin dependent kinases (cdk’s) are a group ofserine/threonine kinases, which rule the transition between successive stages of the cell cycle. theactivity of cdk’s is regulated by multiple mechanisms, including binding to cyclins, which is a broadclass of positive...

Minority ion cyclotron current drive is studied by solving the FokkerPlanck equation in toroidal geometry keeping the ∂/∂v‖-term in the quasilinear operator, hereby including the important effects of the finite orbit widths of the tail ions and the wave-induced spatial drift and diffusion. It has previously been found that the trapped ion current and the current carried by passing ions detrappe...

Solar eruptions are due to a sudden destabilization of force-free coronal magnetic fields. But the detailed mechanisms which can bring the corona towards an eruptive stage, then trigger and drive the eruption, and finally make it explosive, are not fully understood. A large variety of storage-and-release models have been developed and opposed to each other since 40 years. For example, photosphe...

Major histocompatibility complex (MHC) genes have been put forward as a model for studying how genetic diversity is maintained in wild populations. Pathogen-mediated selection (PMS) is believed to generate the extraordinary levels of MHC diversity observed. However, establishing the relative importance of the three proposed mechanisms of PMS (heterozygote advantage, rare-allele advantage and fl...

Measurements of the phases of free jet waves relative to an acoustic excitation, and of the pattern and time phase of the sound pressure produced by the same jet impinging on an edge, provide a consistent model for Stage I frequencies of edge tones and of an organ pipe with identical geometry. Both systems are explained entirely in terms of volume displacement of air by the jet. During edge-ton...

this commentary explores some of the issues raised by gilbert et al.short communication, morality and markets in the nhs. the increasing role of market mechanisms and the changing types of healthcare providers together with the use of choice and competition to drive improvements in quality in the national health service (nhs), all have important ethical implications. in order for the nhs to con...

this paper develops new results on the use of model predictive control to regulate the attitude of a ground station antenna. two degree of freedom az-el pedestal is considered as ground station antenna. permanent magnet synchronous motors are taken into consideration as the best choice for satisfaction of control objectives as actuators. the design is based on a two cascade controller consist o...

In this paper, we developed two noble mechanisms for improving the motions of humanoid robots. The double spherical hip joint provides the equivalent function of waist joints without actually adding them. The backlush clutch is a new drive mechanism for knee joints of humanoid robots, which enables switching between drive and free modes. We developed a humanoid robot equipped with these two mec...

In this paper, using a personal computer (PC), the practical implementation of scalar and vector control methods on a three–phase rotor surface- type permanent magnet synchronous machine drive is discussed. Based on the machine dynamic equations and the above control strategies, two block diagrams are presented first for closed-loop speed controlling of the machine drive/system. Then, the desig...