ôbjectives: non-adherence limits the effectiveness of medications among patients with bipolar disorder. many studies have investigated the predicting factors of non-adherence. this paper aims to present the pattern of adherence in patients with bipolar ï disorder (bïd). methods: seventy six patients with bïd enrolled in a prospective study. the medication possession ratio (mpr) was used to eval...

OBJECTIVE This study was performed to quantify adherence rates to lipid-lowering drug therapy among members of the Canadian Forces (CF) and to identify factors associated with nonadherence. METHODS Pharmacy claims were reviewed for all CF members who received a lipid-lowering drug between April 1 and June 1, 2003. Subjects were categorized as adherent if records indicated consumption of at le...

Adherence to acid suppression therapy is essential in the management of gastroesophageal reflux disease (GERD). Current guidelines suggest that proton pump inhibitors (PPIs) or histamine-2 receptor antagonists (H2RAs) are the mainstays of therapy. The likelihood of adherence to these medications and barriers that may affect adherence and persistence must be considered. A survey done by the Cent...

Antiretroviral therapy has dramatically improved the prognosis for many patients with HIV infection. For many patients who can navigate combinations of drugs and time their doses precisely, these drug regimens typically slow the progression of the disease and lengthen survival. But because these drug regimens are very complex, adherence--the degree to which patients follow medical advice in tak...

Hypertension is growing challenge in Nepalese community which evident from the concern all sectors. Non-adherence to hypertensive medication pose as patients are reluctant start drug despite receiving physician’s advice. Continuing life-long once started, a fear factor that needs dealing urgently.Keywords: Adherence; barrier; hypertension

The demographic development of increasing numbers of elderly patients with chronic diseases requiring continuous polypharmacy represents a challenge for medical care. At present, 30–40% of all German patients .65 years are prescribed four or more different medications, and this number is expected to increase. Nonadherence to medical treatments is an increasingly recognized cause of adverse trea...

AIM This study aimed to describe the prescription pattern of selective serotonin reuptake inhibitors (SSRIs) and serotonin and norepinephrine reuptake inhibitors (SNRIs) in an Italian setting, focusing on therapy duration, switching and adherence. METHOD Historic cohort study, based on administrative databases of three Italian local health-units, was conducted. Patients with a prescription of...

OBJECTIVES to identify the degree of knowledge of people with hypertension concerning the disease and to verify the factors associated with the non-adherence to anti-hypertensive drug therapy. METHOD Cross sectional study, involving 422 people. Data collection took place at their homes, between December 2011 and March 2012, through interviews using the following instruments: Medication Adhere...

Renal Denervation: An Eye Opener Since the publication of the first Symplicity studies in 2009 to 2010, renal sympathetic denervation gained acceptance as a novel treatment of drug-resistant hypertension. The latter has been defined as a blood pressure (BP) >140/90 mm Hg, despite appropriate lifestyle measures plus a diuretic and 2 other antihypertensive drugs belonging to different classes at ...

OBJECTIVE Pharmaceutical treatment of latent tuberculosis infection (LTBI) reduces the risk of progression to active tuberculosis (TB); however, poor adherence tempers the protective effect. We aimed to estimate the health burden of non-adherence, the maximum allowable cost of hypothetical new adherence interventions to be cost-effective and the potential value of existing adherence interventio...