نتایج جستجو برای: drug eruptions
تعداد نتایج: 594352 فیلتر نتایج به سال:
BACKGROUND The aim of this study was to analyze the clinical characteristics of patients with adverse cutaneous drug reactions, which occur when a medicinal product results in cutaneous morbidity. METHODS The study included 308 patients who were diagnosed as having an adverse cutaneous drug reaction during the study period (2007-2009). In 84 cases, histopathologic examination of skin biopsies...
Anticonvulsant Drugs and Severe Adverse Cutaneous Drug Reactions: A Longitudinal Observational Study
Background: Severe Adverse Cutaneous Reactions to Drugs (SACRDs) are skin eruptions due to drugs, which can cause morbidity and morbidity in patients. Objectives: The aim of this study was to determine the offending drug/agents and clinical phenotypes of SACRDs leading to admissions to the hospital. Materials & Methods: We conducted a retrospective cross-sectional study during one year (March...
The study was performed in five hospitals in Bangkok for a period of one year. All in- and outpatients who developed drug eruption from January to December 2001 were enrolled into the study. Physical examinations and complete history-taking were performed by one of the authors. A skin biopsy was done to confirm the diagnosis in every suspected case. Oral challenge test was performed to obtain a...
It remains unknown how autoimmunity is elicited, although many different mechanisms have been involved. There is a major difficulty in establishing a correlation between triggering events and the actual autoimmune disease because of long prodromal period. In this regard, previous studies reported that sera obtained from the acute stage of SJS/TEN and erythema multiforme contain autoantibodies (...
: The present review addresses the literature regarding the sensitivity and specificity of the various diagnostic methods for evaluating non-immediate (ie, occurring more than 1 hour after drug administration) hypersensitivity reactions associated with beta-lactams and other antibiotics, anticonvulsants, heparins, iodinated contrast media, etc. Such reactions include several clinical entities, ...
Thirty three patients with fixed drug eruptions were subjected to provocation tests. Otrimoxazole was the commonest drug responsible, followed by trirnethoprim, Beserol and tinidazole. There was cross sensitivity among sulphonamides. Polys&isitivity was recorded with one case each of Ampicillin and Beserol to Cotrimoxazole (JPMA 37: 1 75, 1987).
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