metabolic syndrome and its pathological sequel, type 2 diabetes are considered as important global health problems. metformin is the most common drug prescribed for patients with this disorder. consequently, understanding the genetic pathways involved in pharmacokinetics and pharmacodynamics of this drug can have a considerable effect on the personalized treatment of type 2 diabetes. in this st...

background and objectives : hepatitis c virus genotyping appears to be vital for predicting the response to antiviral therapy. the present study aimed to analyze the hcv genotypes in relation to persistence or clearance of the virus in residents of hamadan province, west-iran. material and methods : a total of 1159 recorded questionnaires of hcv infected people were evaluated in this prospectiv...

abstract        background and objective: this study was conducted to evaluate epidemiology of risk factors for hepatitis c virus (hcv) transmission, and determine the association of its genotypes with viral load and response to treatment in patients referred to the infectious disease clinic of khorramabad.         methods: the study included patients infected with hepatitis c referred to the i...

Transporters are membrane proteins that are present in all organisms. These proteins control the influx of essential nutrients and ions and the efflux of cellular waste, environmental toxins, and other xenobiotics. Consistent with their critical roles in cellular homeostasis, approximately 2000 genes in the human genome ~7 of the total number of genes code for transporters or transporter-relate...