Objective: Congenital hydronephrosis is a common prenatally diagnosed anomaly associated with an incidence of approximately 0.5-1% in newborns. The purpose of this study was to clarify the value of 99 m diethylenetriamine pentaacetic acid (99mTc-DTPA) in the assessment of renal function impairment of pediatric hydronephrosis. Methods: A total of 48 children with unilateral ureteropelvic junctio...

BACKGROUND AND PURPOSE Diethylenetriamine penta acetic acid (99mTc-DTPA), a substance which indicates glomerular filtration, is distributed equally in blood and tissue after a bolus intravenously injection. Ambulatory Renal Monitor (ARM) is a portable and non invasive device which monitors extracorporeally the clearance of intravenously injected 99mTc-DTPA. We examined correlation between half-...

A three-dimensional magnetic resonance (MR) renographic method to measure single kidney glomerular filtration rate (GFR) and split renal function was developed that is based on renal signal intensity measurements during 2-3 minutes after intravenous injection of a low dose (2 mL or 0.01 mmol/kg) of gadopentetate dimeglumine. In nine subjects, single kidney MR GFR indices correlated well with te...

BACKGROUND The newly developed magnetic-resonance-imaging (MRI) hepatocyte-specific contrast agent, gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA), has different excretion pathways from the conventional MRI contrast agent, gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA). In this study, we compare the enhancement effect of the liver and renal parenchyma betwee...

The aim of this study was to investigate the usefulness of magnetic resonance (MR) imaging in the evaluation of renal function, with particular attention to the effects of water load. Ten healthy volunteers underwent dynamic MR imaging after an injection of gadolinium diethylene-triaminepenta-acetic acid (Gd-DTPA) as a contrast agent to evaluate renal function by the following four methods: the...

To enhance the diagnosis of non-small cell lung cancer (NSCLC), we prepared a dual-modal probe Cy5.5-Tf-Gd-DTPA. Gd-DTPA and near-infrared (NIR) dyes were conjugated to holo-Transferrin (Tf) sequentially, the result of ICP-AES and UV showed 25 Gd ions and 1 Cy5.5 could be loaded per protein, respectively. The calculated longitudinal relaxivity R1 of Cy5.5-Tf-DTPA-Gd was 4.21 mM-1S-1 per Gd whil...

RATIONALE AND OBJECTIVES The purpose of this study was to evaluate the influence of hydration status upon renogram patterns and renal physiological parameters and clarify the differences between DTPA and MAG3 studies in normal volunteers. MATERIAL AND METHODS The study populations were 22 kidneys of 11 volunteers with no history of hypertension or renal disease with normal serum creatinine le...

Two hundred and thirty-nine patients with renal and ureteric calculi associated with renal failure were evaluated for recovery potential before definitive surgery. Ultrasonography was carried out pre-operatively in all, followed by percutaneous nephrostomy (PCN) as an initial management before definitive surgery. Diethylene triamine penta acetic acid (DTPA) scan was done in 125 patients after p...

Introduction: Pyeloplasty has success rate of up to 98%. We believe that paediatric pyeloplasty even in poorly functioning kidney, will result maximum salvage renal function. The aim our study was evaluate the outcome kidneys with PUJO population. Methods: children a GFR < 30 ml / min or 30% differential function on DTPA, who underwent NU hospitals, Bengaluru over period 11 years 2 months, w...

Introduction: Glomerular filtration rate (GFR) is the most important measure for early detection of deterioration of renal function. Patients with diabetic nephropathy need to be intensely monitored with GFR value. Many methods are used to estimate the GFR, all having their own advantages and constraints. The correlation of these methods with each other in patients with diabetic nephropathy nee...