نتایج جستجو برای: dual targeting

تعداد نتایج: 300248  

Journal: :Proceedings of the National Academy of Sciences 2017

Journal: :Journal of Experimental & Clinical Cancer Research 2015

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2013
Michael S Gilmore Francois Lebreton Daria Van Tyne

A leading cause of antibiotic-resistant hospital infection (1), Enterococcus faecalis, decorates its surface with proteins that contribute to its ability to colonize and survive. Several proteins, including Esp (2), aggregation substance (3), a collagen adhesin (4), and a pilin (5), correlate with a particular disease or exacerbate the course of infection in amodel system. In PNAS, Kandaswamy e...

2015
Markus Kunze Johannes Berger

The proper distribution of proteins between the cytosol and various membrane-bound compartments is crucial for the functionality of eukaryotic cells. This requires the cooperation between protein transport machineries that translocate diverse proteins from the cytosol into these compartments and targeting signal(s) encoded within the primary sequence of these proteins that define their cellular...

Journal: :Nephrology Dialysis Transplantation 2023

Abstract Background and Aims Single-loaded nanocarrier that can improve targeting capability drug toxicity compared with free drugs demonstrates a promising strategy for disease treatment. Due to the heterogeneity of injured cells during progression, dose-induced resistance, instability nanocarriers in blood circulation, it is challenging achieve dual different cell subsets as well reducing dos...

Journal: :Sensors & diagnostics 2022

Encapsulation of iron oxide and gold nanoparticles into the bilayer structure transferrin-modified niosomes enables greatly enhanced contamination-free SERS-signals in vitro as well a dual-targeting functionality towards cancer cells.

Objective(s): To investigate the effect of miR-103 on the angiogenesis of ischemic stroke rats via targeting vascular endothelial growth factor (VEGF) at the molecular level. Materials and Methods: Rat models had received the middle cerebral artery occlusion (MCAO) or sham operation before grouping, and cell models of oxygen-glucose deprivation (OGD) were performed. FITC-dextran, matrigel, and ...

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