We introduce a formal model of explanatory dialogue called EDS. We extend this model by including argumentation capacities to facilitate knowledge acquisition in inconsistent knowledge bases. To prove the relevance of such model we provide the dalek (DiALectical Explanation in Knowledge-bases) framework that implements this model. We show the usefulness of the framework on a real-world applicat...

In order to compile an inventory of national data sources for drug utilization research (DUR) in Argentina and verify publicly available sources, we performed a cross-sectional study that sought identify provincial databases use. July 2020, searched the websites government institutions, carried out systematic query bibliographic “drug research” conducted Argentina, survey with local experts. Da...

OBJECTIVE The aim of this study was to further elucidate the mechanisms of dual-phase technetium-99m methoxyisobutylisonitrile (Tc-MIBI) parathyroid imaging by exploring the association between early uptake results (EUR), delayed uptake results (DUR), and the retention index (RI) in dual-phase Tc-MIBI parathyroid imaging and P glycoprotein (P-gp), multidrug resistance-associated protein 1 (MRP1...

OBJECTIVES New designs have improved the ability of flexible ureteroscopes to assess the upper urinary tract. However, limitations of tip deflection may interfere with diagnosis and treatment of lower pole renal pathologic features and smaller working channels may impair irrigant flow. Our purpose was to compare the new flexible ureteroscopes with prior models to determine whether engineering a...

OF GAMMA-RAY BURSTS E. E. Fenimore D436 Los Alamos National Laboratory, Los Alamos, NM 87545, USA email: [email protected] Received..........; accepted............ ABSTRACT We have averaged bright BATSE bursts to uncover the average overall temporal and spectral evolution of gamma-ray bursts (GRBs). We align the temporal structure of each burst by setting its duration to a standard duration, w...

The present study determined whether 0.8g/kg bodyweight sago ingested before (Pre-Sago) or during (Dur-Sago) exercise under warm-humid conditions (30 ± 2°C, 78 ± 3 % RH; 20 km·h-1 frontal airflow) conferred a performance and/or physiological benefit compared to a control (Control) condition. Eight trained, male cyclists/triathletes (45 ± 4 y, VO2peak: 65 ± 10 ml·kg-1·min-1, peak aerobic power: ...

We described earlier a novel mode of regulation of Hsp104, a cytosolic chaperone directly involved in the refolding of heat-denatured proteins, and designated it delayed upregulation, or DUR. When Saccharomyces cerevisiae cells grown at the physiological temperature of 24 degrees C, preconditioned at 37 degrees C, and treated briefly at 50 degrees C were shifted back to 24 degrees C, Hsp104 exp...