BACKGROUND Chronic inflammation may be involved in combat-related post-traumatic stress disorder (PTSD) and may help explain comorbid physical diseases. However, the extent to which combat exposure per se, depression, or early life trauma, all of which are associated with combat PTSD, may confound the relationship between PTSD and inflammation is unclear. METHODS We quantified interleukin (IL...

Life traumatic experiences are major health problems in different communities. Early trauma exposures such as physical and sexual abuse, and midlife traumatic events like exposing to disasters are predisposing and precipitating risk factors for many psychiatric disorders, although many people facing to trauma may not show any problematic symptoms and are quite resilient. Neuropsychiatric eviden...

Nurse practitioners regularly treat primary care patients with trauma histories. By incorporating trauma-informed into practice, nurse can enhance the provision of clinical and, ultimately, improve patient health outcomes. This brief report demonstrates how to actively incorporate principles and practices 4R framework realize prevalence trauma, recognize patients’ signs symptoms, respond in a m...

The purpose of this article is to view the evidence to support a connection between early childhood trauma and subsequent cancer. This trauma has a critical period and must occur within the first 7 to 8 years of life and its long latency period will await the necessary trigger, in later life, which will activate the cancer. The important part played by repressed emotions will be explored, in th...

OBJECTIVE Childhood trauma is associated with negative perinatal health outcomes including mood disorders and shorter gestation. However, effects of early life exposures on maternal biology are poorly delineated. This study examined associations between childhood trauma and inflammation, as well as the mediating role of obesity in this relationship. METHOD This study examined a racially diver...

life traumatic experiences are major health problems in different communities. early trauma exposures such as physical and sexual abuse, and midlife traumatic events like exposing to disasters are predisposing and precipitating risk factors for many psychiatric disorders, although many people facing to trauma may not show any problematic symptoms and are quite resilient. neuropsychiatric eviden...

BACKGROUND Although some studies have found high rates of early childhood trauma in Chronic Fatigue Syndrome (CFS), the role of early trauma in this condition remains controversial. METHODS This study examined the prevalence of early childhood trauma and its impact on daily fatigue and pain levels over a 14-day period in a sample of 90 carefully screened CFS patients using a diary method appr...

Animals, including humans, require a highly coordinated and flexible system of social behavior and threat evaluation. However, trauma can disrupt this system, with the amygdala implicated as a mediator of these impairments in behavior. Recent evidence has further highlighted the context of infant trauma as a critical variable in determining its immediate and enduring consequences, with trauma e...

Trauma, especially early life trauma, is a risk factor for the development of both posttraumatic stress disorder and psychosis. The goal of the present study was to determine specific associations between exposure to childhood abuse, PTSD symptoms, and current psychotic disorder. Subjects were recruited from a public, urban hospital (N=328, >90% African American). Psychotic disorders were measu...