The EAST protein of Drosophila is a component of an expandable extrachromosomal domain of the nucleus. To better understand its function, we studied the dynamics and localization of GFP-tagged EAST. In live larval salivary glands, EAST-GFP is highly mobile and localizes to the extrachromosomal nucleoplasm. When these cells are permeabilized, EAST-GFP rapidly associated with polytene chromosomes...

Ronghui Pan,a,b A. Daniel Jones,b,c and Jianping Hua,d,1 aMichigan State University–Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824 bDepartment of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan 48824 cDepartment of Chemistry, Michigan State University, East Lansing, Michigan 48824 d Plant Biology Depa...

East Asia encompasses a wide variety of environments, peoples, cultures and languages. Although this review focuses on East Asia, no geographic region can be considered in isolation in terms of human population history, and migrations to and from East Asia have had a major impact. Here, we review the following topics: the initial colonization of East Asia, the direction of migrations between so...

1Department of Biostatistics and Epidemiology, East Tennessee State University, USA 2Department of Community and Behavioral Health, College of Public Health East Tennessee State University, USA 3Center for Nursing Research, East Tennessee State University, USA 4James H Quillen College of Medicine, East Tennessee State University, USA 5Department Tennessee of Education, Coordinated School Health...

BACKGROUND AND PURPOSE In Rivaroxaban Once Daily Oral Direct Factor Xa Inhibitor Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF) trial, rivaroxaban was noninferior to dose-adjusted warfarin in preventing stroke or systemic embolism among patients with nonvalvular atrial fibrillation at moderate to high stroke risk. Because of dif...

Cancer is a major cause of mortality and morbidity throughout the world, including the countries of North-East and South-East Asia. Assessment of burden through cancer registration, determination of risk and protective factors, early detection and screening, clinical practice, interventions for example in vaccination, tobacco cessation efforts and palliative care all should be included in compr...

PURPOSE Peripheral refraction is commonly used to infer retinal shape. Because of the different prevalence of myopia in the white compared with East Asian populations, peripheral refraction along the horizontal meridian was compared in white and East Asian young adults with emmetropic, low myopic, and moderately myopic refractive errors. METHODS Thirty-five white and 37 East Asian subjects we...

Some 20 years after reunification, the contrast between East and West Germany offers a natural experiment for studying the degree of persistence of Communist-era family patterns, the effects of economic change, and fertility postponement. After reunification, period fertility rates plummeted in the former East Germany to record low levels. Since the mid-1990s, however, period fertility rates ha...