Abstract Background Effective antibiotic alternatives are urgently needed in the poultry industry to control disease outbreaks. Phage therapy mainly utilizes lytic phages kill their respective bacterial hosts and can be an attractive solution combating emergence of resistance livestock. Methods Five hundred four, one-day-old broilers (Ross 308) were allotted 1 4 treatment groups a completely ra...

In this digital era, machine learning is a technology that in demand by organizations and individuals. the age of data information, ability to process efficiently needed. As amount grows, there are various problems learning. One them with increasing data, class imbalance also often found. Class condition where dominates another class, one example case when positive value has less number than ne...

A study was conducted to evaluate the therapeutic efficacy of bacteriophage and the antibiotic enrofloxacin individually and in combination to treat colibacillosis. The experimental design was a 2 x 2 x 2 factorial with 8 treatments and 4 replicate pens of 10 birds. The treatments were 1) control, 2) unchallenged birds treated with bacteriophage, 3) enrofloxacin, or 4) the combination; 5) birds...

Shiga toxin (Stx) is the principal virulence factor during Shiga toxin-producing Escherichia coli (STEC) infections. We have previously reported the inactivation of bacteriophage encoding Stx after treatment with chitosan, a linear polysaccharide polymer with cationic properties. Cationic antimicrobial peptides (cAMPs) are short linear aminoacidic sequences, with a positive net charge, which di...

results electron microscopy showed mrsa phages’ resemblance to members of the family siphoviridae, serogroups a and f. they exhibited a latent period of 70 minutes and a relatively burst size of 2,400 plaque-forming units (pfu)/infected cell. the titer of the phages was determined to be 3 × 109 pfu/ml using the by dla technique. conclusions in this study, two phages from the family siphoviridae...

By marker rescue of bacteriophage SP02 sus mutants with purified bacteriophage SP02 DNA fragments, 11 of the 17 known bacteriophage SP02 sus loci were assigned to discrete DNA fragments. The left-most genetic locus, susA, was found to reside near one bacteriophage SP02 terminus (EcoRI-C1 fragment), whereas the right-most genetic locus, susP, was found to reside near the other bacteriophage SP02...

Bacteriophage vB_Eco_swan01 was isolated from an ornamental pool using Escherichia coli MG1655 as the host. Bacteriophage vB_Eco_swan01 has limited similarity with other known phages at the nucleotide level and likely represents a new bacteriophage species within the Tunavirinae.