Nanotechnology plays an important role in the development of biosensors. The sensitivity and performance of biosensors are improved by using nanomaterials through new signal transduction technologies. The development of tools and processes used to fabricate, measure and image nanoscale objects, has led to the development of sensors that interact with extremely small molecules that need to be an...

a sensitive monitoring of biological analytes, such as biomolecules (protein, lipid, dna and rna), and biological cells (blood cell, virus and bacteria), is essential to assess and avoid risks for human health. nanobiosensors, analytical devices that combine a biologically sensitive element with a nanostructured transducer, are being widely used for molecular detection of biomarkers associated ...

Triangular silver nanoparticles ( approximately 100 nm wide and 50 nm high) have remarkable optical properties. In particular, the peak extinction wavelength, lambda(max) of their localized surface plasmon resonance (LSPR) spectrum is unexpectedly sensitive to nanoparticle size, shape, and local ( approximately 10-30 nm) external dielectric environment. This sensitivity of the LSPR lambda(max) ...

The Ag nanoparticle based localized surface plasmon resonance (LSPR) nanosensor yields ultrasensitive biodetection with extremely simple, small, light, robust, and low-cost instrumentation. Using LSPR spectroscopy, the model system, biotinylated surface-confined Ag nanotriangles, was used to detect less than one picomolar up to micromolar concentrations of streptavidin. Additionally, the monito...

The BRODERICK PROBE® encompasses several formulations of carbon-based biosensors, patented by City University of New York (CUNY) and assigned to CUNY and in part to NYU Medical Center of NYU; all patents describing in detail, the series of nanobiosensors are held by Eazysense Nanotechnologies Incorporated in New York State in concert with CUNY Technology Commercialization Office (TCO). Nanobios...

The field of BioNano/Micro System applies both nanotechnology and MEMS (microelectromechanical systems) to solve biological and medical problems as well as biological structures and principles to solve engineering MEMS problems. In this paper, some technical efforts to develop nanobiotechnology, focusing on nanobiosensor, microfluidics and lab-on-a-chip are briefly reviewed. In order to ensure ...