Hypertension is a common risk factor for peripheral arterial disease (PAD). Guidelines suggest treating PAD patients to a blood pressure <130/80 mm Hg; therefore, our objective was to explore whether attainment of this target blood pressure is associated with improved outcomes. We performed a post hoc analysis of the INternational VErapamil-SR/Trandolapril STudy, a randomized clinical trial, wh...

Peripheral arterial disease (PAD) produces abnormal gait and disproportionately affects older individuals. The current study investigated PAD gait biomechanics in younger (<65 yr) and older (>/=65 yr) subjects. The study included 61 patients with PAD (31 younger, age: 57.4 +/- 5.3 yr, and 30 older, age: 71.9 +/- 5.2 yr) and 52 nondisabled age-matched control subjects. Patients with PAD were tes...

Abstract: Lower extremity peripheral artery disease (PAD) is frequently underdiagnosed, in part because of the wide variety of leg symptoms manifested by patients with PAD and in part because of the high prevalence of asymptomatic PAD. In primary care medical practices, 30% to 60% of patients with PAD report no exertional leg symptoms and ≈45% to 50% report exertional leg symptoms that are not ...

Men and women with lower extremity peripheral arterial disease (PAD) have higher levels of inflammatory biomarkers than those without PAD. Observational studies link higher levels of several inflammatory biomarkers, including C-reactive protein (CRP), interleukin-6, tumor necrosis factor-alpha, and soluble adhesion molecules, to 1 or more of the following outcomes in people with PAD: more sever...

BACKGROUND National guidelines recommend the use of secondary prevention modalities for patients with peripheral artery disease (PAD) and coronary artery disease. The effect of prior PAD on the treatment and outcomes of patients with acute coronary syndromes (ACS), however, is not well characterized. The objectives of this study were to assess treatment practices and hospital outcomes in patien...

background: the relationships between adiponectin and clinical outcomes in hemodialysis (hd) patients remain highly controversial. meanwhile, the association between adiponectin and the peripheral artery disease (pad) has not been well studied in hd patients without diabetic mellitus. materials and methods: the ankle-brachial index was measured in hd patients. adiponectin levels in 105 hd patie...

(This is part 2, continued from “Use of harsh Wafer Probing to Evaluate Traditional Bond Pad Structures”). Goals for circuit under pad (CUP) in aluminum – silicon dioxide (Al – SiO2) based IC pad structures include the design of metal interconnects in all layers beneath the pad Al, and the ability to withstand harsh probing and wirebonding stress without SiO2 cracking, without deforming or bend...

Background: Periampullary duodenal diverticulum (PAD) is associated with increased incidence of biliary pathology presumably due to dysfunction of the sphincter of Oddi and ascending bacterial infection from the duodenum. Aim: to compare ERCP performance characteristics and outcomes in patients with (study group) and without PAD (control group). Materials and Methods: This is retrospective coho...

BACKGROUND AND OBJECTIVES Peripheral arterial disease (PAD) is a known predictor of cardiovascular morbidity and mortality among hemodialysis patients. Although ankle-brachial BP index (ABI) is a simple and reliable test for PAD screening, its sensitivity has been suggested to decrease among dialysis patients. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS We performed a cross-sectional outpat...

Background: Peripheral arterial disease is known to be associated with the diabetes and ankle-brachial pressure index (ABPI) can be used to screen such patients having PAD. Aims & Objective: To highlight the application of ankle brachial pressure index as a routine procedure and to assess the feasibility of using ABPI in detecting PAD in the patients of diabetes mellitus. Material and Methods: ...