نتایج جستجو برای: embedded prostate tissues
تعداد نتایج: 395844 فیلتر نتایج به سال:
PURPOSE The Cooperative Prostate Cancer Tissue Resource (CPCTR) is a National Cancer Institute-supported tissue bank that provides large numbers of clinically annotated prostate cancer specimens to investigators. This communication describes the CPCTR to investigators interested in obtaining prostate cancer tissue samples. EXPERIMENTAL DESIGN The CPCTR, through its four participating institut...
Background Despite years of studies and effort, the best strategies for treating prostate cancer minimizing complications treatment remain unanswered questions. This gap in knowledge is partially due to inability dissect complex heterogeneous tumor microenvironment (TME) immune compartment. Spatially resolved molecular profiling sections will enhance our understanding these complexities; Howeve...
introduction: htlv-1 , the first known human retrovirus belongs to oncovirus subfamily of retroviruses. the major characteristic of htlv-1 is its highly restricted geographic prevalence. northern part of khorasan is an endemic region of htlv-1 infection. epidemiological studies can help in designing preventive programs for htlv-1 infection. the aim of this study was the establishment of a pcr t...
The sperm protein associated with the nucleus in the X chromosome (SPANX) gene family encode for proteins that are not only expressed in germ cells, but also in a number of tumors. In addition, SPANX genes map in an interval of the X chromosome (namely, Xq27), which has been found to be associated with familial prostate cancer by linkage analysis. The aim of this study was therefore to evaluate...
The aim of the present study was to identify a new prostate cancer‑associated gene and analyze its expression pattern. Comprehensive expression analysis of expressed sequence tags (ESTs) and microarray data and serial analysis of gene expression (SAGE) were conducted to screen in silico for candidate prostate cancer‑associated genes. Reverse trans...
PURPOSE The ErbB1 and ErbB2 receptors have been implicated in prostate cancer progression, but less is known about the role and biology of other ErbB receptor family members in prostate cancer. The aim of this study was to analyze the expression and localization of ErbB3 in prostate tissues and prostate cancer cell lines. EXPERIMENTAL DESIGN Immunohistochemistry of ErbB3 was done on prostate ...
Background: MiRNAs are one of the most important genetic regulators that regulate more than 50 percent of the human genome. MiR-124-a-3 is a tumor suppressor miRNA which its expression dramatically reduced in prostate cancer tumor cells. Since miRNA binding to the transcript of target genes by seed sequence, any mutations and changes in this region could be effective on its performance and iden...
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