نتایج جستجو برای: endoderm
تعداد نتایج: 3230 فیلتر نتایج به سال:
The anterior visceral endoderm (AVE) has attracted recent attention as a critical player in mouse forebrain development and has been proposed to act as "head organizer" in mammals. However, the precise role of the AVE in induction and patterning of the anterior neuroectoderm is not yet known. Here we identified a 5'-flanking region of the mouse Otx2 gene (VEcis) that governs the transgene expre...
In vertebrates the endoderm germ layer gives rise to most tissues of the digestive tract and controls head and heart morphogenesis. The induction of endoderm development relies on extracellular signals related to Nodals and propagated intracellularly by TGFbeta type I receptors ALK4/Taram-A. It is unclear, however, whether Nodal/ALK4/Taram-A signalling is involved only in the specification of e...
T H E initial report in this series (Finnegan, 1961) emphasized the role of the endoderm in the postgastrula differentiation of the hypomeric mesoderm in Ambystoma punctatum. The effect of the endoderm appeared to be modified when the mass of mesoderm involved was increased and, under the in vitro experimental conditions employed, the endoderm did not influence the splanchnic layer of the hypom...
Human pluripotent stem cell (hPSC) differentiation typically yields heterogeneous populations. Knowledge of signals controlling embryonic lineage bifurcations could efficiently yield desired cell types through exclusion of alternate fates. Therefore, we revisited signals driving induction and anterior-posterior patterning of definitive endoderm to generate a coherent roadmap for endoderm differ...
Mesoderm of precardiac and cardiac region ('cardiac' mesoderm) of chick, quail and mouse embryos could induce hepatic epithelium in the endoderm of the anterior half of young quail or chick embryos (anterior endoderm) in vitro as well as in vivo. No species specificity in the induction of hepatic epithelium by the 'cardiac' mesoderm could be observed. The hepatic induction, was controlled stric...
The cellular events that take place during reconstruction of larval forms from dissociated embryonic cells of the starfish are investigated by thick and thin sections. Dissociated cells reaggregate, form an external epithelium (ectoderm), internal epithelial vesicles (endoderm), the blastocoel and the mesenchyme. The internal vesicles continue to fuse until there is only one large one suspended...
Embryogenesis in ascidians is known to be of the mosaic type, a property that suggests the presence of cytoplasmic factors in the egg which are responsible for specification of the developmental fates of early blastomeres. Endoderm cells are present in the trunk region of tadpole larvae, and these cells specifically express alkaline phosphatase (AP). Endoderm cells originate exclusively from bl...
Embryoid bodies formed from teratocarcinoma stem cells differentiate an outer layer consisting of parietal and visceral endoderm or of visceral endoderm exclusively. We have previously shown that when these embryoid bodies are plated on collagen-coated substrates a parietal endoderm-like cell migrates onto the substrate, whereas all of the visceral endoderm remains associated with the stem cell...
During mouse gastrulation, endoderm cells of the dorsal foregut are recruited ahead of the ventral foregut and move to the anterior region of the embryo via different routes. Precursors of the anterior-most part of the foregut and those of the mid- and hind-gut are allocated to the endoderm of the mid-streak-stage embryo, whereas the precursors of the rest of the foregut are recruited at later ...
Hepatogenic potency of the endoderm is detectable in the anterior half of the endoderm of quail embryos older than 2-somite stage when endodermal fragments are cultured with or without heterologous chick mesenchymes, in the coelomic cavity of 3-day chick embryos. On the other hand, the posterior half of the endoderm never has hepatogenic potency. The hepatogenic potency of the endoderm is gradu...
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