A new metric for the evaluation of model performance in the field of virtual screening and quantitative structure-activity relationship applications is described. This metric has been termed the power metric and is defined as the fraction of the true positive rate divided by the sum of the true positive and false positive rates, for a given cutoff threshold. The performance of this metric is co...

A new metric for the evaluation of model performance in the field of virtual screening and quantitative structure– activity relationship applications is described. This metric has been termed the power metric and is defined as the fraction of the true positive rate divided by the sum of the true positive and false positive rates, for a given cutoff threshold. The performance of this metric is c...

Microcosm experiments were conducted to quantify carbon isotope fractionation during aerobic biodegradation of n-alkanes (from C3 to C10) and monoaromatic hydrocarbons in unsaturated alluvial sand. In single compound experiments with n-alkanes, the largest enrichment factor was obtained for propane ( 10.8 ± 0.7‰). The magnitude of the enrichment factor decreased with increasing number of carbon...

Genome-wide binding data from transcription factor ChIP-seq experiments is the best source of information for inferring the relative DNA-binding affinity of these proteins in vivo. However, standard motif enrichment analysis and motif discovery approaches sometimes fail to correctly identify the binding motif for the ChIP-ed factor. To overcome this problem, we propose 'central motif enrichment...

the alborz coal basin is located in northern part of iran. the coal deposits of shahrood in eastern alborz, zirab in central alborz and abyek in western alborz were studied as typical coalfields of the basin. shemshak formation which is the main coal-bearing sequence was formed during the triassic-jurassic in the basin. it consists of sandstone, siltstone, shale and claystone, which variedly al...

it is dawn clear that empowered employees in public sector perform a critical role in their organizational service quality. by the same token, currently competitive advantages stem from employees’ high self-confidence and their commitment toward the goals rather than application of high technologies. this study summarizes twenty influencing factors on employees empowerment including information...