Eosinophilic cellulitis (EC) is described as erythematous plaques with perivascular and interstitial infiltration of eosinophils. EC is associated with various skin disorders, and occurs in adverse drug reactions to many medications (1). A previous report described a patient with EC who was found to have increased interleukin (IL)-5-producing circulating T cells (2), suggesting the coexistence ...

A 12-year-old girl presented with an erythematous, papular, occasionally pruritic eruption covering both her legs. Her main complaint was aesthetic. The rash consisted of grouped red papules 10 ^ 15 mm in size. The patient was afebrile and reported no arthralgia or any other systemic symptoms. She denied any recent arthropod bite, viral or fungal infection, or ingestion of any kind of drug. The...

Background Wells syndrome belongs in diseases with eosinophilic involvement in specific organs (eg, skin, lungs). Peripheral eosinophilia (mild or moderate-profound) is present in more than 50%. May be idiopathic, associated with drugs, or even associated with myeloproliferative, immunological or infectious diseases. Reported about 80 incidents worldwide. Has an excellent prognosis. It tends to...

Eosinophilic cellulitis (Wells' syndrome) is an uncommon condition of unknown etiology. Wells' syndrome is usually seen in adulthood but very rare in childhood. Although pathogenesis of the disease is not very clear, it is a hypersensitivity reaction developing against a variety of exogenous and endogenous antigenic stimuli. Paraphenylenediamine is a strong allergen frequently used as a tempora...

A 53-year-old man was admitted to the hospital with a diagnosis of cellulitis and osteomyelitis. Twenty-four days after the initiation of daptomycin and sulbactam/ampicillin, he developed a fever and pulmonary infiltration. Bronchoalveolar lavage revealed a high number of eosinophils, while an intracutaneous test revealed positivity for daptomycin. The patient improved after discontinuing antim...

Eosinophilic cellulitis or Wells syndrome is an uncommon skin condition of unknown etiology that can occur alone or associated with other conditions. Typically, it presents with recurrent pruritic, erythematous and edematous plaques, but it can also show clinical polymorphism. Besides the cutaneous lesions, patients can experience systemic manifestations like fever, malaise, arthralgia and peri...

T his peripheral blood is from a 3-month-old male patient with a prior diagnosis of GM1 gangliosidosis type I, who was admitted with fever and leukocytosis. There is a family history of 2 siblings with GM1 gangliosidosis. Cellulitis was diagnosed and successfully treated with antibiotics. This photomicrograph depicts the typical peripheral blood findings in GM1 gangliosidosis: a vacuolated lymp...

purpose: to evaluate the epidemiology of orbital and preseptal cellulitis in patients admitted to labbafinejed medical center from 1997 to 2007. methods: hospital records of patients were reviewed. personal and clinical characteristics of the patients together with results of treatment and complications of the disease were evaluated. results: during the study period, 93 patients including 54 ca...