PURPOSE To evaluate the effect of hypothyroidism on erectile function and sperm parameters. MATERIALS AND METHODS This study was conducted on 24 patients with hypothyroidism and 66 normal individuals. Serum levels of hormones, including thyroid stimulating hormone (TSH), thyroxin (T4), follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin (PRL), and testosterone, were measur...

OBJECTIVE • To investigate the regulatory role of androgen in VIP-mediated erectile effect. Androgen is essential for physiological erection. Vasoactive intestinal polypeptide (VIP) is an important erectile neurotransmitter. While previous studies demonstrated that VIP expression in the penis was androgen-independent, it remains controversial whether androgen has any effect on VIP-mediated erec...

Extracorporeal shock wave therapy improves erectile function in patients with Peyronie's disease. However, erectile dysfunction still persists in many cases. We aimed to investigate the effects of extracorporeal shock wave therapy plus tadalafil 5 mg once daily in the management of patients with Peyronie's disease and erectile dysfunction not previously treated. One hundred patients were enroll...

OBJECTIVES To investigate the role of low-intensity extracorporeal shockwave therapy in the treatment of erectile dysfunction. METHODS This was a double-blinded, single-center, prospective, randomized, placebo-controlled trial. After a 2-week phosphodiesterase type 5 inhibitor washout period, patients were assessed with Sexual Health Inventory for Men, International Index of Erectile Function...

PURPOSE To evaluate the effect of postoperatively administering a low daily dose of tadalafil on the erectile function of patients who underwent a nerve-sparing radical prostatectomy (NSRP) due to localized prostate cancer (PCa). MATERIALS AND METHODS Of 138 patients, who underwent NSRP due to PCa between 2012 and 2014, 55 patients who had not had pre-operative erectile dysfunction (ED) were ...

Sexual desire typically persists when men grow older although their ability to attain and maintain erections sufficient to permit satisfactory sexual intercourse gradually declines. Decreasing erectile quality is a common age-related problem affecting the lives of both men and their partners. Lifestyle plays an important role in the onset of erectile quality problems, and timely improvements su...

Sexual desire typically persists when men grow older although their ability to attain and maintain erections sufficient to permit satisfactory sexual intercourse gradually declines. Decreasing erectile quality is a common age-related problem affecting the lives of both men and their partners. Lifestyle plays an important role in the onset of erectile quality problems, and timely improvements su...

OBJECTIVE Erectile dysfunction affects quality of life and is a common dysfunction in drug abusers. The aim of this study was to evaluate the frequency of erectile dysfunction in drug abusers on methadone maintenance therapy to reduce this drug side effect in the future studies. METHODS This cross-sectional study was conducted with two hundred addicted individuals on methadone maintenance the...

OBJECTIVE To examine the role of pelvic floor exercises as a way of restoring erectile function in men with erectile dysfunction. PATIENTS AND METHODS In all, 55 men aged > 20 years who had experienced erectile dysfunction for > or = 6 months were recruited for a randomized controlled study with a cross-over arm. The men were treated with either pelvic floor muscle exercises (taught by a phys...

BACKGROUND Men with erectile dysfunction often have concurrent medical conditions. Conversely, men with these conditions may also have underlying erectile dysfunction. The prevalence of unrecognized erectile dysfunction in men with comorbidities commonly associated with erectile dysfunction was determined in men invited to participate in a double-blind, randomized, placebo-controlled trial of s...