It has been suggested that infection with hepatitis C virus may be associated with the development of lichen planus and that geographical area may be an important factor affecting the relative risk. The present 2-centre, prospective, epidemiological study investigates this possible association in north west England. A total of 45 patients with classical and/or erosive mucous membrane lichen pla...

Background: Oral lichen planus is a potentially malignant disorder. One of the malignant transformation markers is cancer stem cells. One of the proposed marker for the detection of cancer stem cells's in head and neck cancer is aldehyde dehydrogenase. Recently it is shown that aldehyde dehydrogenase 1 expression in tissue samples is associated with oral lichen planus malignant transformation. ...

AIM Many studies have suggested that a lesion originally diagnosed as oral lichen planus (OLP) has different possibilities of undergoing malignant transformation in time, although these findings remain a controversial issue; for example, some studies reported different values of potential malignancy of OLP. INTRODUCTION World Health Organization (WHO) classifies OLP as a "potentially malignan...

Chronic ulcerative dermatitis (CUS) is characterized by painful exacerbating and remitting oral erosions and ulcerations. A very characteristic direct immunofluorescence (DIF) pattern differentiates CUS from other immune-mediated oral vesiculo-erosive conditions. The clinical and histopathological features of CUS are very similar to erosive oral lichen planus. A middle-aged woman had CUS confir...

Abstract Vulvovaginal lichen planus is a type of chronic inflammatory dermatosis the vulva, usually seen as part widespread planus. The common clinical types vulval include papulosquamous, erosive, and pigmented types. Hypertrophic vulva rare entity. We report case hypertrophic

Lichen sclerosus, lichen planus, and lichen simplex chronicus are three of the most common non-neoplastic epithelial disorders of the vulva. Lichen sclerosus is characterized by intense vulvar itching and can affect men and women of all ages, but it manifests most commonly in postmenopausal women. Patients with lichen sclerosus have an increased risk of developing squamous cell carcinoma, and t...

Background and objective: Given the postulated the role of inflammation and possible contribution of lymphangiogenesis in oral lichen planus, this study aimed to assess any associated presence of VEGFR-3. Material and Methods: This cross-sectional study was performed on 52 formalin fixed and paraffin embedded blocks of oral lichen planus (pathological diagnosis based on Modified WHO criteria), ...

BACKGROUND The association of lichen planus with hepatitis C (HCV) has been widely reported in the literature. However, there are wide geographical variations in the reported prevalence of HCV infection in patients with lichen planus. This study was conducted to determine the frequency of hepatitis C in Iranian patients with lichen planus at Razi hospital, Tehran. METHODS During the years 199...

Background: Oral lichen planus (OLP) is a common inflammatory disease of unknown origins. Recent studies have considered nutritional factors concerning the pathogenesis of many autoimmune disorders. The objective of the present study was to investigate the plasma levels of magnesium (Mg), calcium (Ca), zinc (Zn), copper (Cu), and iron (Fe) in this disorder. Methods: Included in this observation...