Erythema nodosum (EN) is a delayed-type hypersensitivity reaction that most often presents as erythematous, tender nodules on the shins. Common triggers for EN include infection, drugs, pregnancy, malignancy, and inflammatory conditions, such sarcoidosis or gastrointestinal diseases; however, many cases are idiopathic. We present clinical case of 12 y.o girl with associated EBV.

Erythema nodosum was first distinguished from other forms of erythema by Willan (1808), and Hebra (1860) amplified Willan's account of the condition as follows: " . . . tumours of a pale red colour, raised above the level of the skin, and either semi-globular or oval in form. These swellings are tender on pressure, and are observed chiefly on the lower limbs. In some cases, the outbreak of this...