In this study, the acetylcholinesterase inhibition and in vitro and in vivo antioxidant activities of Ganoderma lucidum grown on germinated brown rice (GLBR) were evaluated. In antioxidant assays in vitro, GLBR was found to have strong metal chelating activity, DPPH, ABTS, hydroxyl and superoxide radical scavenging activity. Cell-based antioxidant methods were used, including lipid peroxidation...

The erythrocyte levels of the antioxidant enzymes SOD and GPx, and serum levels of antioxidants vitamins β-carotene and β­ tocopherol were estimated in various types of brain tumors, and were compared with the levels in controls. Statistically significant (P<.001) diminished levels of βcarotene, β-tocopherol, SOD and GPx, were observed in all the brain tumor patients as compared to controls. Ma...

Background. Prostate cancer is the most common noncutaneous cancer and second leading cause of cancer-related mortality in men in the US. Growing evidence suggests that oxidative stress is involved in prostate cancer. Methods. In this study, thioredoxin 1 (Trx 1), an enzyme and subcellular indicator of redox status, was measured in prostate biopsy tissue from 55 men from the North Carolina-Loui...

background: this study was performed to investigate the adverse effects of acute lead intoxication on hemogram, erythrocyte osmotic fragility and oxidant/antioxidant status and the probable ameliorating effect of silymarin in comparison to d-penicillamine. methods: forty-eight albino rats were divided in 8 groups and received the following treatments in a 10 day experiment in shahid chamran uni...

anaplasma ovis infections can cause severe anemia in the acute phase of the disease. in order to investigate the alterations of erythrocyte protective antioxidant mechanisms associated with anemia in sheep experimentally infected with a. ovis, 100 ml heparinized blood was collected from splenectomised sheep that showed 6% a. ovis parasitemia. inoculums of 20 ml blood were administered intraveno...

This study was conducted to investigate firstly, the oxidative stress and erythrocyte hemolysis induced by exposure to 2450 MHz continuous wave microwave (MW), which is the carrier of signals emitted by cellular phones. Secondly to evaluate the possible protective role of grape seed extract. Male rats were randomly divided into four groups, the first group was considered as control, the second ...

BACKGROUND The oxidative stress theory of aging is one of the most widely acknowledged theories of aging. The intake of fruits and vegetables with antioxidant power is associated with a reduced incidence of many chronic diseases of aging. OBJECTIVE The effects of ingesting garlic on plasma and erythrocyte antioxidant parameters of elderly subjects were investigated in this study. METHODS 13...

Chemotherapeutic agents used in patients with cancer cause to generate the enormous amounts of free radicals associated with cell injury. In this study we assess the effects of chemotherapy regimen on oxidant/antioxidant status in patients with acute myeloid leukemia (AML). 38 newly diagnosed patients with acute myeloid leukemia were recruited in this study. All patients received cytarabine and...

Objective(s) Bone is a dynamic tissue that is continuously renewed throughout life by the process of bone remodeling. Antioxidant system might be involved in the pathogenesis of bone loss, so the aim of this study was to evaluate the total antioxidant capacity (TAC), vitamin C and vitamin E levels of plasma besides measuring enzymatic antioxidants, superoxide dismutase (SOD), catalase (CAT) an...

The aim of the present study was to determine whether there was any correlation between serum thyroid hormones, lipids, lipoproteins and the activities of erythrocyte superoxide dismutase (SOD) and glutathione peroxidase (GPX) in adult nonpregnant uniparous Iranian pure bred fat-tailed ewes. Blood samples (10 mL) were taken from the jugular vein of 30 clinically healthy Iranian adult nonpregnan...