Current treatment strategies against the development of corrosive esophageal strictures remain unsatisfactory. Thus, the aim of the present study was to investigate the efficacy of keratinocyte growth factor, in the form of palifermin, for the prevention of stricture development following esophageal caustic injuries in a rat model. A total of 32 female Wistar albino rats were divided into four ...

BACKGROUND Aim of our study is to highlight technical details in pedicled right colon interposition locally in cases of long segment corrosive esophageal stricture. Lesion results from cicatrization of burns wound inflicted by chemicals. Restoration of swallowing is of paramount importance. MATERIALS AND METHODS It was a retrospective study involving adult and adolescent patients who had surg...

Introduction. Ingestion of corrosive substances may lead to stricture formation in esophagus as a late complication. Full thickness injury seems to exterminate tissue stem cells of esophagus. Mesenchymal stem cells (MSCs) can differentiate into specific cell lineages and have the capacity of homing in sites of injury. Aim and Methods. We aimed to investigate the efficacy of MSC transplantation,...

introduction: complications of caustic ingestion swallowing in children of singe to gullet severe  stricture and andoscopic actions and multiple surgeries is different that increase the risk of gastrointestinal perforation and gastrointestinal malignancies ..... because acid substances have  bad taste and these are tissue coalescence in location of contact thus attribute alkali make lose of inj...

Accidental corrosive ingestion is one of the common problems causing serious esophageal strictures in children. The acute phase treatment has a great effect on stricture development. In this study we aim to present our experience in the management of caustic ingestion, particularly during the acute phase. From January 1990 to January 2005, 296 children were admitted to our clinic with caustic i...

Introduction: Complications of caustic ingestion swallowing in children of singe to gullet severe  stricture and andoscopic actions and multiple surgeries Is different that increase the risk of gastrointestinal perforation and gastrointestinal malignancies ..... Because Acid substances have  bad taste and these are tissue coalescence in location of contact thus attribute alkali make lose of ...

Introduction. Burns patients are vulnerable to hyperthermia due to sepsis and SIRS and to hypothermia due to heat loss during excision surgery. Both states are associated with increased morbidity and mortality. We describe the first use of a novel esophageal heat exchange device in combination with a heater/cooler unit to manage perioperative hypothermia and postoperative pyrexia. Material and ...

BACKGROUND Surgery is the criterion standard for the treatment of severe burns and of late sequels after ingestion of corrosive agents, but long-term outcome is unknown. METHODS Patients who underwent surgery between 1987 and 2006, for the treatment of severe caustic burns (group I, n = 268) or of late sequels (group II, n = 79) were included in the study. Survival and functional outcomes wer...

purpose: to evaluate the prevalence of acute ocular chemical injuries in patients referred to labbafinejad medical center (lmc) over a period of one year. methods: all patients with chemical burns referred to lmc emergency ophthalmology service were included in the study. demographic characteristics and information regarding the burn were obtained. visual acuity assessment and slit lamp examina...

Ingestion of a corrosive substance can produce severe injury to the gastrointestinal tract and can even result in death. The degree and extent of damage depends on several factors like the type of substance, the morphologic form of the agent, the quantity, and the intent. In the acute stage, perforation and necrosis may occur. Long-term complications include stricture formation in the esophagus...