BACKGROUND Gastroesophageal reflux disease (GERD) is one of the most common gastrointestinal pathology in infants and young children. Ultrasonography (US) has been considered to be a reliable diagnostic tool for GERD but the severity of GERD and the clinical implications based on imaging findings has not been evaluated. AIMS To compare the diagnostic value of lower esophageal US with that of ...

Background: Rett syndrome is a neurodevelopmental disorder associated with gastroesophageal reflux disease (GERD) and dysphagia. Objective: Correlate esophageal motility disturbances with symptoms of GERD and dysphagia and with MECP2 gene mutations in children with Rett syndrome. Study Design: Thirty-two consecutive Rett patients with a mean (range) age of 6.2 (2.3-14) years with prior history ...

BACKGROUND Nighttime reflux has been shown to be associated with esophageal mucosal injury, complications, and extra-esophageal manifestations. However, few studies have assessed the impact of gastroesophageal reflux on reported quality of sleep and quality of sleep on gastroesophageal reflux. AIMS The aims of this study were (1) to determine the correlation between the severity of gastroesop...

The etiology of esophageal mucosal injury is complex, since it may involve the reflux of gastric acid, bile acid, and pancreatic juice, external factors such as drugs and alcohol, or functional factors such as esophagogastric motility. The mechanism of esophageal mucosal injury has gradually been understood at the molecular biological level. It is particularly important that pro-inflammatory fa...

OBJECTIVES The gastroenterology literature suggests that gastroesophageal reflux disease (GERD) is often associated with obesity. The National Institutes of Health uses body mass index (BMI) to identify patients who are overweight (BMI 25-30) or obese (BMI > 30). The aim of this study was to determine whether there is a relationship between laryngopharyngeal reflux (LPR) and elevated BMI. STU...

BACKGROUND/AIMS Gastroesophageal reflux disease (GERD) is diagnosed based on symptoms of heartburn and regurgitation but is a heterogeneous condition which can be subclassified according to endoscopy and esophageal reflux monitoring. The aim of this study was to identify differences in demographic characteristics and reflux symptom patterns among patients with various spectrum of GERD. METHOD...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 aim : this study was designed to investigate about findings of impedance ph-monitoring in patients with atypical symptoms of gerd. background : the routine treatment with proton pump inhibitors is not very effective in patients with atypical symptoms of gastro-esophageal reflux disease (gerd). it may be due to non-acid ref...

conclusions b. oleracea demonstrated similar anti-inflammatory properties to omeprazole in rats with gerd. however, omeprazole also demonstrated genotoxic and cytotoxic effects in rats without gerd. results rats with gerd developed esophagitis and esophageal squamous cell carcinoma. b. oleracea and omeprazole-treated gerd rats presented significantly decreased inflammation in relation to non-tr...

Gastroesophageal reflux disease (GERD) is defined by the presence of troublesome symptoms resulting from the reflux of gastric contents. The prevalence of GERD is increasing globally. An incompetent lower esophageal sphincter underlies the pathogenesis of GERD. Proton pump inhibitors (PPIs) form the core of GERD management. However, a substantial number of patients do not respond well to PPIs. ...

BACKGROUND The nature of the relationship between Helicobacter pylori and reflux esophagitis (RE) is not fully understood. In addition, the effect of H. pylori eradication on RE and gastroesophageal reflux disease (GERD) is unclear. This study was designed to investigate the relationship between H. pylori infection and the grade of GERD in patients with reflux symptoms. METHODS Between Januar...