BACKGROUND AND AIM The familial aggregation of Barrett's esophagus, adenocarcinoma of the esophagus, and adenocarcinoma of the gastroesophageal junction, jointly termed familial Barrett's esophagus, may represent a complex genetic trait. The aim of this study was to determine the proportion of patients with these diseases who have familial Barrett's esophagus. METHODS Information on gastroeso...

BACKGROUND/AIMS In recent years, changes in the definition of Barrett's esophagus have resulted in some difficulties in its diagnosis. Very few epidemiological data on Barrett's esophagus and erosive esophagitis in Turkey are available in the literature. The aim of this study was to determine the prevalence of Barrett's esophagus and erosive esophagitis in a tertiary referral center in Turkey. ...

BACKGROUND The distal esophagus harbors a complex bacterial population. We hypothesized that a better understanding of bacterial communities in the esophagus would facilitate understanding of the role of bacteria in esophageal disease. Here, we investigated bacterial composition in the distal esophagus in subjects with a normal esophagus, reflux esophagitis, and Barrett's esophagus. METHODS T...

Escherichia coli (E. coli) is a rod-shaped, gram-negative bacillus normally found in the lower gastrointestinal tract and is part of the normal intestinal flora. In hospital settings, E. coli most commonly causes urinary tract infections. Respiratory tract infections due to E. coli are uncommon, though there have been several published reports that chronicle E. coli pneumonia in the pediatric i...

congenital esophageal atresia needs to be surgically corrected as soon as possible. some will present with post surgical stricture that needs to be dilated by a balloon dilator. this procedure is difficult in premature born due to infant esophageal size and availability of equipments. we herby report the first case in a premature infant with post surgical esophageal stricture of esophageal atre...

malignant melanoma of the esophagus is a rare tumor with poor prognosis. the survival of patients is generally less than one year after diagnosis. a case of primary malignant melanoma of the esophagus is presented, who after radical resection of the tumor, is in excellent health, with no evidence of disease 14 months after surgery.

introduction primary malignant esophageal melanoma makes up 0.1% to 0.2% of all esophageal malignancies. most physicians assume malignant melanoma as a skin originated neoplasm, however this type of melanoma can occur anywhere in the gastrointestinal tract especially in the esophagus. thus, it is essential to consider malignant melanoma in differential diagnosis of any esophagus masses. case pr...

esophagus cancer is the eighth most common cancer worldwide and particularly high in an area extending from the southern border of the caspian sea in iran across central asia to china. since information about this mysterious disease is poor, proteomics may be solving this enigma. altering gene expression in cancer cell is a remarkable indicator can be detected by proteomics techniques and bioin...

The precursor metaplastic mucosal lesion that predisposes for esophageal adenocarcinoma is Barrett's esophagus. Because the signal transduction events that occur in Barrett's esophagus are poorly understood, this study aimed at generating a comprehensive description of cellular kinase activity in Barrett's esophagus, normal squamous esophagus, and gastric cardia to gain more insight into the pa...