Background and Purpose We tested the hypothesis that body mass, waist-to-hip circumference ratio, physical inactivity, diabetes, hyperglycemia, and fasting insulin are each positively associated with asymptomatic carotid artery wall thickness. Methods Average intimal-medial carotid wall thickness (an indicator of atherosclerosis) was measured noninvasively by B-mode ultrasonography in cross-sec...

the management of carotid artery stenosis reduces the risk of stroke and its related deaths.   management options include risk factor modification and medical therapy, carotid endarterectomy (cea), and carotid artery stenting (cas). although several randomized controlled trials (rcts), mostly conducted in late-1980s and mid-1990s, have proved cea to be effective in the prevention of ipsilateral...

BACKGROUND AND PURPOSE Carotid atherosclerotic thrombosis is an important cause of ischemic stroke in Western countries. The therapeutic efficacy of either aspirin or heparin alone in this setting is still controversial. Recently we developed a simple model, the "clamp" method, to induce acute carotid mural thrombosis in vivo in guinea pigs. In this study, we used this model to evaluate the ant...

BACKGROUND AND PURPOSE We tested the hypothesis that body mass, waist-to-hip circumference ratio, physical inactivity, diabetes, hyperglycemia, and fasting insulin are each positively associated with asymptomatic carotid artery wall thickness. METHODS Average intimal-medial carotid wall thickness (an indicator of atherosclerosis) was measured noninvasively by B-mode ultrasonography in cross-s...

objectives in this study, we aimed to investigate the changes in brain lipidomics following prolonged and intermittent ischemic preconditioning. materials and methods two groups underwent bilateral common carotid artery occlusion either intermittently (for 3 continuous periods within a timeframe of 20 minutes, releasing 3 consecutive times, yielding a total of 9 minutes (intermittent bilateral ...

BACKGROUND Plaque rupture with subsequent thrombosis is recognised as the underlying pathophysiology of most acute coronary syndromes. Thus, direct thrombus visualisation in vivo may be beneficial for both diagnosis and guidance of therapy. We sought to test the feasibility of imaging acute thrombosis in vivo using optical coherence tomography (OCT) in an experimental thrombosis animal model. ...

background: common carotid arterial stiffness can be assessed during carotid arterial ultrasonography, but its association with brachial stiffness, a well-defined cardiovascular risk factor, has not been clarified. the aim of this study was to examine the relationship between common carotid artery and brachial artery stiffness. methods: the static pressure-strain elastic modulus of the common c...

vertebrobasilar insufficiency is the cause of cerebrovascular accidents in 20% of cases. there are few reports regarding spectral doppler indices (sdis) of vertebral arteries (vas) normal blood flow. the objective of this study was to provide basic reference data about sdis of vas normal blood flow separately and in comparison with internal carotid arteries (icas) and common carotid arteries (c...

Two major mechanisms are involved in cerebral ischemia (Mohr et al., 1997). Cerebral perfusion failure may occur as the result of flow reduction mediated by stenosis or occlusive vascular damage such as that arising from atheroma plaques that affect the carotid bulb. Perfusion failure affects the distal territories, and it is known as a watershed infarction. The second mechanism of cerebral isc...

The preferred treatment of various internal carotid aneurysms deemed surgically inaccessible involves the occlusion of the carotid artery with subsequent thrombosis of the aneurysm. Carotid occlusion can be accomplished surgically either by abrupt ligation or with the use of a controlled gradual occlusive device such as a Selverstone clamp [1 , 2]. Recently a transcatheter detachable balloon sy...