نتایج جستجو برای: ethynylestradiol 17α

تعداد نتایج: 1121  

2013
Isabel Cabas Elena Chaves-Pozo Alicia García-Alcázar José Meseguer Victoriano Mulero Alfonsa García-Ayala

Pollutants have been reported to disrupt the endocrine system of marine animals, which may be exposed through contaminated seawater or through the food chain. Although 17α-ethynylestradiol (EE₂), a drug used in hormone therapies, is widely present in the aquatic environment, current knowledge on the sensitivity of marine fish to estrogenic pollutants is limited. We report the effect of the diet...

Journal: :Organic & biomolecular chemistry 2014
Ben Zhang Peter Y Zavalij Lyle Isaacs

We report the synthesis and X-ray crystal structures of three acyclic CB[n]-type molecular containers (2a, 2h, 2f) that differ in the charge on their solubilizing groups (SO3(−), OH, NH3(+)). The X-ray crystal structures of compounds 2h and 2f reveal a self-folding of the ArOCH2CH2X wall into the cavity driven by π–π interactions, H-bonds and ion–dipole interactions. The need to reverse this se...

Journal: :Journal of water and health 2012
Kathleen Schenck Laura Rosenblum Thomas E Wiese Larry Wymer Nicholas Dugan Daniel Williams Heath Mash Betty Merriman Thomas Speth

Estrogenic compounds have been shown to be present in surface waters, leading to concerns over their possible presence in finished drinking waters. In this work, two in vitro human cell line bioassays for estrogenicity were used to evaluate the removal of estrogens through conventional drinking water treatment using a natural water. Bench-scale studies utilizing chlorine, alum coagulation, ferr...

Journal: :Environmental science & technology 2015
Spurti U Akki Charles J Werth Scott K Silverman

We used in vitro selection to identify new DNA aptamers for two endocrine-disrupting compounds often found in treated and natural waters, 17β-estradiol (E2) and 17α-ethynylestradiol (EE). We used equilibrium filtration to determine aptamer sensitivity/selectivity and dimethyl sulfate (DMS) probing to explore aptamer binding sites. The new E2 aptamers are at least 74-fold more sensitive for E2 t...

Journal: :Environmental toxicology and chemistry 2011
Ben D Giudice Thomas M Young

Municipal biosolids are commonly applied to land as soil amendment or fertilizer as a form of beneficial reuse of what could otherwise be viewed as waste. Balanced against this benefit are potential risks to groundwater and surface water quality from constituents that may be mobilized during storm events. The objective of the present study was to characterize the mobilization of selected endocr...

2017
Michael B. Stout Frederik J. Steyn Michael J. Jurczak Joao-Paulo G. Camporez Yi Zhu John R. Hawse Diana Jurk Allyson K. Palmer Ming Xu Tamar Pirtskhalava Glenda L. Evans Roberta de Souza Santos Aaron P. Frank Thomas A. White David G. Monroe Ravinder J. Singh Grace Casaclang-Verzosa Jordan D. Miller Deborah J. Clegg Nathan K. LeBrasseur Thomas von Zglinicki Gerald I. Shulman Tamara Tchkonia James L. Kirkland

Aging is associated with visceral adiposity, metabolic disorders, and chronic low-grade inflammation. 17α-estradiol (17α-E2), a naturally occurring enantiomer of 17β-estradiol (17β-E2), extends life span in male mice through unresolved mechanisms. We tested whether 17α-E2 could alleviate age-related metabolic dysfunction and inflammation. 17α-E2 reduced body mass, visceral adiposity, and ectopi...

2014
Sarah Roberts Christopher Higgins John McCray

Conventional onsite wastewater treatment system design relies on a septic tank and soil treatment unit (STU) for treatment of wastewater and integration of the final effluent into the environment. Organic water contaminants (OWCs), chemicals found in pharmaceutical drugs, detergents, surfactants, and other personal care and cleaning products, have been observed in septic tank effluent and the e...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید