background and objective: organisms producing ctx-m β-lactamases are emerging as a source of resistance to oxyiminocefalosporins such as ceftriaxone and ceftazidime. however, the laboratory detection of these strains is not well defined. in this study, phenotypic assay for screening of extended-spectrum β-lactamases producing strains and molecular assay for the identification of ctx-m β-lactama...

Knowledge of antimicrobial resistance patterns in E. coli, the predominant pathogen associated with urinary tract infections (UTI) is important as a guide in selecting empirical antimicrobial therapy. Methods: To describe the antimicrobial susceptibility of E. coli associated with UTI in a major university hospital in Tehran (Iran), seventy-six clinical isolates of E. coli were studied for susc...

Aeromonas species, aquatic Gram-negative bacilli, distributed globally and ubiquitously in the natural environment, may be implicated in a variety of human diseases. They can produce various β-lactamases which confer resistance to a broad spectrum of β-lactams, and therefore in vitro susceptibility testing must be used to guide antimicrobial therapy. However, conventional in vitro susceptibilit...

knowledge of antimicrobial resistance patterns in e. coli, the predominant pathogen associated with urinary tract infections (uti) is important as a guide in selecting empirical antimicrobial therapy. methods: to describe the antimicrobial susceptibility of e. coli associated with uti in a major university hospital in tehran (iran), seventy-six clinical isolates of e. coli were studied for susc...

beta-Lactamases are the main cause of bacterial resistance to penicillins and cephalosporins. Class A beta-lactamases, the largest group of beta-lactamases, have been found in many bacterial strains, including mycobacteria, for which no beta-lactamase structure has been previously reported. The crystal structure of the class A beta-lactamase from Mycobacterium fortuitum (MFO) has been solved at...

background: ampc and esbls as mediated-plasmid extended spectrum β-lactabases are the main factors of resistance to extended-spectrum cephalosporins in enterobacteriacea especially e. coli and will follow treatment failure, high costs of treatment in human and economic losses in the poultry industry. objectives: the purpose of this study was to screen and study the faecal e. coli isolates produ...