Antipsychotic-induced extrapyramidal adverse effects are well recognized in the context of first-generation antipsychotic drugs. However, the introduction of second-generation antipsychotics, with atypical mechanism of action, especially lower dopamine receptors affinity, was met with great expectations among clinicians regarding their potentially lower propensity to cause extrapyramidal syndro...

MOTOR SYMPTOMS OF SCHIZOPHRENIA Schizophrenia is typically conceived as an illness characterized by positive, negative, and cognitive symptoms. However, most schizophrenia patients also display a wide range of symptoms characterized by aberrant motor functioning. Symptoms of schizophrenia that fit this description are catatonic features, the motoric neurological soft signs (NSS), extrapyramidal...

This case is of 54-year-old female with catatonic schizophrenia, characterized by treatment resistance to the pharmacotherapy with olanzapine, risperidone, flunitrazepam, and ECT. Olanzapine and risperidone and flunitrazepam did not improve her catatonic and psychotic symptoms, and induced the extrapyramidal symptoms. The effects of ECT did not continue even for a month. However, the treatment ...

Sertraline has been considered to be a relatively safe selective serotonin reuptake inhibitor for adolescents for a long time. We report herein a case of a 16-year-old Chinese boy with depression who experienced extrapyramidal-like effects, for example, facial spasm, upper limb dystonia, akathisia, and other disturbed behaviors, while being treated with sertraline 200 mg per day. His movement s...

Extrapyramidal symptoms (EPSs) are common adverse reactions to antipsychotics in patients with schizophrenia. The purpose of this study was investigate the effects edible horticultural therapy (EHT) on EPSs schizophrenic patients. This assessed changes psychopathological and extrapyramidal schizophrenia before after participating a six-session EHT. Forty patients, recruited from Wuhan Wudong Ho...