نتایج جستجو برای: factor viii and factor ix inhibitor

تعداد نتایج: 16983528  

Journal: :The Journal of biological chemistry 1987
S Rimon R Melamed N Savion T Scott P P Nawroth D M Stern

Endothelium provides a specific binding site for Factor IX/IXa which can propagate activation of coagulation by promoting Factor IXa-VIII-mediated activation of Factor X. In this report the endothelial cell Factor IX/IXa binding site has been identified and the coagulant function of the receptor blocked. Studies using [3H]Factor IX derivatized with the photoaffinity labeling agent N-succinimidy...

Faranoush , Mohammad , Karimi , Katayoun , Managhchi , Mohammad-Reza , Rezaiei–Hemami , Mohsen , Roushan , Nader , Toogeh , Gholamreza , Zarrabi , Fariba ,

Background: The development of inhibitors is a complication factor replacement therapy in hereditary factor VIII deficiency. Several management options are available for the treatment of inhibitor. Rituximab, a monoclonal antibody against CD20, reduces inhibitor level in rare bleeding disorders. The aim of this study was to evaluate the effectiveness of rituximab in lowering or eliminating the ...

Journal: :Blood 1987
D B Brettler F Brewster P H Levine A Forsberg S Baker J L Sullivan

Because there have been reports that factor IX concentrate is less immunosuppressive and therefore factor IX users have less immunologic aberrations, we have studied a group of 22 patients with hemophilia B and six patients with factor VIII deficiency and high titer inhibitors with respect to lymphocyte numbers and function, human immunodeficiency virus (HIV) serology, and factor usage. This gr...

Journal: :Transfusion Medicine and Hemotherapy 2018

Journal: :Blood 1978
M B Hultin Y Nemerson

We studied the activation of factor X by the intrinsic pathway of blood coagulation using a new assay of factor X activation. When factor X tritiated in its sialic acid residues is activated, activation can be measured by the release of tritiated activation peptide, and the initial rate of activation can be determined under varying conditions. In the presence of phospholipid and calcium ions, f...

پایان نامه :وزارت بهداشت، درمان و آموزش پزشکی - دانشگاه علوم پزشکی و خدمات بهداشتی درمانی مشهد - دانشکده دندانپزشکی 1391

چکیده : مقدمه وهدف : درمان دندانهای نکروتیک نابالغ از موارد پیچیده ای است که دردرمانهای اندودنتیک با آن مواجه می‏شویم. مطالعات اخیرنشان داده است که امکان رژنریشن پالپ در فضای کانال وادامه تشکیل ریشه در دندان های نکروتیک با اپکس باز وجود دارد. هدف از این مطالعه برسی بیان فاکتور های vegf و viii دررژنریشن پالپ دندان های نکروزه با اپکس بالغ ونا بالغ با استفاده از prp به روش ایمونوهیستوشیمی بوده اس...

Journal: :Blood 1990
I M Nilsson E Berntorp O Zettervall B Dahlbäck

We recently described tolerance induction with factor VIII/IX, cyclophosphamide, and high-dose intravenous IgG in hemophilia A or B patients with coagulation inhibitory antibodies. Circulating noninhibitory antibodies complexed with factor IX have been demonstrated in tolerant hemophilia B patients. Similar findings are now described in six tolerant hemophilia A patients. Complexes between fact...

لیلا بردبار, ,

Transfusion of blood products from an infected person with AIDS, is meant to infect recipient. Blood Products such as whole blood, red blood cells, platelets, plasma, frozen blood precipitate, factor VIII, factor IX, can be infected with HIV. Transmissions from blood factors can be seen in plasma from thousands of donors that were collected in a container and were used to treat hemophilia. Bloo...

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