A Two-Level Fractional Factorial design was employed to develop and optimize the combination of demographic characteristics that has the greatest effect on the spread of HIV in the South African population. HIV prevalence (dependent variable) was found to be highly sensitive to changes in the mother’s age (15-55years) and level of education (Grades 0-13) (independent variables), using the 2006 ...

The objective of the current study was to develop and optimize a novel lyophilized liposomal formulation anticancer agent carmustine, or bis-chloroethyl nitrosourea (BCNU) for prolonged release that could overcome dose-dependent side effects improve its bioavailability at site action. optimization done using 32 factorial design approach wherein soya phosphatidylcholine (SPC) cholesterol (CH) as...